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Thyrotropin-Releasing Hormone (TRH), Free Acid

Cat. No. Size Price Figures
RP10114-5 mg
 		5 mg
$ 24.00
MSDS:  20080626211035  (PDF)


References:
  • Jin H, et al. Thyrotropin-releasing hormone is induced in the left ventricle of rats with heart failure and can provide inotropic support to the failing heart. Circulation. May 2004; 109(18): 2240-2245.
  • Kagabu Y, et al. Effects of thyrotropin-releasing hormone and its metabolites, Cyclo(His-Pro) and TRH-OH, on growth hormone and prolactin synthesis in primary cultured pituitary cells of the common carp, Cyprinus carpio. Gen. Comp. Endocrinol. Sep 1998; 111(3): 395-403.
  • Deshpande SB and Warnick JE. Analogs of thyrotropin-releasing hormone in potentiating the spinal monosynaptic reflex in vitro. Eur. J. Pharmacol. Dec 1994; 271(2-3): 439-444.
Full Name
Thyrotropin-Releasing Hormone (TRH), Free Acid
Sequence
(one-letter code)		 pEHP
Sequence
(three-letter code)		{pGLU}{HIS}{PRO}
DescriptionTRH free acid is derived from Thyrotropin Releasing Hormone (TRH), and the latter could cause the release of Thyroid Stimulating Hormone (TSH) from the pituitary and was isolated in pure form and the structure determined. They are different functionally, such as stimulation of GTPase depended on occupancy of the TRH receptor; half-maximal increases in GTPase activity required 46 nM TRH and 25 nM [N3-methyl-His]TRH, but the TRH free acid was inactive.
FormulaC16H21N5O5
M.W.363.37
Cas24769-58-2
Purity> 95%
StorageStore at -20°C. Keep tightly closed.
* For Non-Clinical Research Use Only *
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RP10109 peptide : Prepro Thyrotropin-Releasing Hormone (TRH) (178-199)1 mg
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RP10112peptide : Thyrotropin-Releasing Hormone (TRH)5 mg
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