| Cat. No. |
Size |
Price |
Figures |
|---|
RP10129-0.5 mg
| 0.5 mg | $ 57.00 | MSDS: 20080710033450 (PDF)
References:
- Rudolph C, et al. Oligomers of the arginine-rich motif of the HIV-1 TAT protein are capable of transferring plasmid DNA into cells. J. Biol. Chem. Mar 2003; 278(13): 11411-11418.
- Ignatovich IA, et al. Complexes of Plasmid DNA with Basic Domain 47–57 of the HIV-1 Tat Protein Are transferred to Mammalian Cells by Endocytosis-mediated Pathways. J. Biol. Chem. Oct 2003; 278(43): 42625-42636.
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| Full Name | | HIV-I TAT Protein Peptide |
|
| Alias |
HIV-1 TAT Protein Peptide; HIV1 TAT Protein Peptide, HIV-1 TAT; HIV1 TAT |
Sequence
(one-letter code) |
YGRKKRRQRRR |
Sequence
(three-letter code) | {TYR}{GLY}{ARG}{LYS}{LYS}{ARG}{ARG}{GLN}{ARG}{ARG}
{ARG} |
|---|
| Description | HIV-1 TAT Protein Peptide is known to be a protein and particle transduction domain (PTD) and at the same time to comprise a nuclear localization function (NLS). Oligomers of the TAT (47-57) peptide compact plasmid DNA to nanometric particles and stabilize DNA towards nuclease degradation. At optimized vector compositions, these peptides mediate gene delivery to cells in culture six to eight times more efficiently than poly-L-arginine or the mutant TAT2-M1. |
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| Formula | C64H118N32O14 |
|---|
| M.W. | 1559.9 |
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| Purity | > 95% |
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| Storage | Store the peptide at -20°C. Keep container tightly closed. Store in a cool dry place. |
