| |
Substance P  |
|
|

| Cat. No. |
Size |
Price |
Figures |
RP10178-5 mg
| 5 mg | $ 43.00 | HPLC: 20090204024923 (PDF) MS: 20090204024952 (PDF) MSDS: 20070511025917 (PDF) DATASHEET: 20080130210055 (DOC) EXAMPLE:
 Zoom
References:
- Wick EC, et al. Transient receptor potential vanilloid 1, et al. calcitonin gene-related peptide, and substance P mediate nociception in acute pancreatitis. Am J Physiol Gastrointest Liver Physiol. May 2006;290(5):G959-969.
- Allen JW, et al. Safety Evaluation of Intrathecal Substance P-Saporin, a Targeted Neurotoxin, in Dogs. Toxicol Sci. May 2006;91(1):286-298.
- Gontijo JR, et al. CGRP activates renal pelvic substance P receptors by retarding substance P metabolism. Hypertension. Jan 1999;33(1 Pt 2):493-498.
|
|---|
| Full Name | |
Sequence (one-letter code) |
RPKPQQFFGLM-NH2 | Sequence (three-letter code) | {ARG}{PRO}{LYS}{PRO}{GLN}{GLN}{PHE}{PHE}{GLY}{LEU} {MET}-NH2 | | C-Terminal | NH2 |
|---|
| Description | Substance P is found in the gut and in the brain. It is responsible for a number of excitatory effects on both central and peripheral neurons. Substance P contracts smooth muscle, constricts bronchioles, and increases capillary permeability. When released from afferent nerves, Substance P causes a neurogenic inflammatory response, including mast cell degranulation. It's an NK-1 agonist; a potent vasodilator and hypotensive agent; it induces salivation; it's a putative neurotransmitter in sensory (pain) afferents. |
|---|
| Solubility | Soluble in water (1 mg/ml) |
|---|
| Formula | C63H98N18O13S1 | | M.W. | 1347.63 | | Cas | 33507-63-0 |
|---|
| Purity | > 95% | | Storage | Store the peptide at -20°C. Keep container tightly closed. |
| * For Non-Clinical Research Use Only *
 |
1 |
Peptide Services: GenScript's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
|
2 |
Standard Peptide Synthesis: GenScript offers quality peptides at the most competitive prices in the industry, starting at $2.56 per amino acid. GenScript FlexPeptideTM technology can synthesize peptide as long as 200 amino acids, a world record for such technology.
|
3 |
Peptide Modifications: GenScript offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
|
4 |
Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.
|
Our customer service is available 24 hours a day, Monday through Friday. You may contact us any time for assistance.
|
|