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Substance P

Cat. No. Size Price Figures
RP10178-5 mg
 		5 mg
$ 43.00
HPLC:  20090204024923  (PDF)
MS:  20090204024952  (PDF)
MSDS:  20070511025917  (PDF)
DATASHEET:  20080130210055  (DOC)

EXAMPLE:
Substance P Example
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References:
  • Wick EC, et al. Transient receptor potential vanilloid 1, et al. calcitonin gene-related peptide, and substance P mediate nociception in acute pancreatitis. Am J Physiol Gastrointest Liver Physiol. May 2006;290(5):G959-969.
  • Allen JW, et al. Safety Evaluation of Intrathecal Substance P-Saporin, a Targeted Neurotoxin, in Dogs. Toxicol Sci. May 2006;91(1):286-298.
  • Gontijo JR, et al. CGRP activates renal pelvic substance P receptors by retarding substance P metabolism. Hypertension. Jan 1999;33(1 Pt 2):493-498.
Full Name
Substance P
Sequence
(one-letter code)		 RPKPQQFFGLM-NH2
Sequence
(three-letter code)		{ARG}{PRO}{LYS}{PRO}{GLN}{GLN}{PHE}{PHE}{GLY}{LEU}
{MET}-NH2
C-TerminalNH2
DescriptionSubstance P is found in the gut and in the brain. It is responsible for a number of excitatory effects on both central and peripheral neurons. Substance P contracts smooth muscle, constricts bronchioles, and increases capillary permeability. When released from afferent nerves, Substance P causes a neurogenic inflammatory response, including mast cell degranulation. It's an NK-1 agonist; a potent vasodilator and hypotensive agent; it induces salivation; it's a putative neurotransmitter in sensory (pain) afferents.
SolubilitySoluble in water (1 mg/ml)
FormulaC63H98N18O13S1
M.W.1347.63
Cas33507-63-0
Purity> 95%
StorageStore the peptide at -20°C. Keep container tightly closed.
* For Non-Clinical Research Use Only *
Related Products:
CodeNameSizePrice 
RP10179peptide : Substance P (1-4)1 mg
$ 24.00
RP10180 peptide : Substance P (1-7)1 mg
$ 24.00
RP10181peptide : Substance P (1-9)1 mg
$ 24.00
RP10182 peptide : Substance P (7-11)1 mg
$ 24.00
RP10184peptide : Substance P, Methyl Ester5 mg
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RP10185 peptide : Substance P, Free Acid5 mg
$ 43.00
RP10207peptide : [Nle11]-Substance P1 mg
$ 24.00
RP10208 peptide : [Pro9]-Substance P0.5 mg
$ 24.00
RP10210peptide : [Sar9]-Substance P1 mg
$ 33.00
RP10213 peptide : [Tyr8]-Substance P1 mg
$ 24.00




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