GenScript Catalog Peptide: Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (RP10245)

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Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat

Cat. No.

Size

Price

Figures

RP10245-1 mg

1 mg

$ 142.50

HPLC:  20071220011618  (PDF)
MS:  20080903051219  (PDF)
MSDS:  20071223212305  (PDF)

References:

Teuscher C, et al. Evidence that the Y chromosome influences autoimmune disease in male and female mice. Proc. Natl. Acad. Sci. U.S.A. May 2006; 103(21): 8024-8029.
Komiyama Y, et al. IL-17 plays an important role in the development of experimental autoimmune encephalomyelitis. Jul 2006; 177(1): 566-573.
Bannerman PG, et al. Motor neuron pathology in experimental autoimmune encephalomyelitis: studies in THY1-YFP transgenic mice. Brain. Aug 2005; 128(Pt 8): 1877-1886.

Full Name

Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat

Sequence
(one-letter code)

MEVGWYRSPFSRVVHLYRNGK

Sequence
(three-letter code)

{MET}{GLU}{VAL}{GLY}{TRP}{TYR}{ARG}{SER}{PRO}{PHE}
{SER}{ARG}{VAL}{VAL}{HIS}{LEU}{TYR}{ARG}{ASN}{GLY}
{LYS}

Description

Myelin oligodendrocyte glycoprotein (MOG) is found exclusively in the CNS, where it is localized on the surface of myelin and oligodendrocyte cytoplasmic membranes and has been implicated as an important autoantigen in multiple sclerosis (MS). This peptide induces severe chronic experimental autoimmune encephalomyelitis in transgenic mice.

Solubility

Recommended to reconstitute the lyophilized MOG in sterile 18 MΩ-cm H₂O of not less than 100 µg/ml. This solution can then be further diluted to other aqueous solutions.

Formula

C₁₁₈H₁₇₇N₃₅O₂₉S₁

M.W.

2581.98

Cas

163913-87-9

Purity

95%

Storage

Store at -20°C

* For Non-Clinical Research Use Only *

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