| Cat. No. |
Size |
Price |
Figures |
|---|
RP10268-1 mg
| 1 mg | $ 23.75 | MSDS: 20080923045603 (PDF)
References:
- Richie-Jannetta R, et al. Dimerization of cGMP-dependent protein kinase Ibeta is mediated by an extensive amino-terminal leucine zipper motif, and dimerization modulates enzyme function. J. Biol. Chem. Dec 2003; 278(50): 50070-50079.
- Taylor MK, et al. Autoinhibition and isoform-specific dominant negative inhibition of the type II cGMP-dependent protein kinase. Oct 2002; 277(40): 37242-37253.
- Pawliczak R, et al. p11 expression in human bronchial epithelial cells is increased by nitric oxide in a cGMP-dependent pathway involving protein kinase G activation. J. Biol. Chem. Nov 2001; 276(48): 44613-44621.
|
|---|
RP10268-5 mg
| 5 mg | $ 80.75 |
|---|
| Full Name | | Arg-Lys-Arg-Ser-Arg-Ala-Glu |
|
Sequence
(one-letter code) |
RKRSRAE |
Sequence
(three-letter code) | {ARG}{LYS}{ARG}{SER}{ARG}{ALA}{GLU} |
|---|
| Description | RKRSRAE is a selective substrate for PKG with a strong preference for PKG Ia (Km=59 μM) over PKG II (Km=305 μM). The Vmax/Km of the peptide substrate is significantly increased by peptide-546, a PKG activator. |
|---|
| Solubility | The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents. |
|---|
| Formula | C35H67N17O11 |
|---|
| M.W. | 902.1 |
|---|
| Purity | > 95% |
|---|
| Storage | Store the peptide at -20°C |
| Notes | This peptide makes an excellent substrate for cGMP protein kinase. |
|---|
