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Autocamtide 2

Cat. No. Size Price Figures
RP10271-1 mg
 		1 mg
$ 48.00
HPLC:  20060721145615  (PDF)
MS:  20060721145554  (PDF)
MSDS:  20080630235606  (PDF)


References:
  • Ishida A, et al. Critical amino acid residues of AIP, a highly specific inhibitory peptide of calmodulin-dependent protein kinase II. FEBS Lett. May 1998; 427(1): 115-118.
  • Tatone C, et al. Possible role for Ca(2+) calmodulin-dependent protein kinase II as an effector of the fertilization Ca(2+) signal in mouse oocyte activation. Mol. Hum. Reprod. Aug 2002; 8(8): 750-757.
  • Aromolaran AA, Blatter LA. Modulation of intracellular Ca2+ release and capacitative Ca2+ entry by CaMKII inhibitors in bovine vascular endothelial cells. Am. J. Physiol., Cell Physiol. Dec 2005; 289(6): C1426-C1436.
Full Name
Autocamtide 2
Alias Autocamtide2; AC-2; AC2
Sequence
(one-letter code)		 KKALRRQETVDAL
Sequence
(three-letter code)		{LYS}{LYS}{ALA}{LEU}{ARG}{ARG}{GLN}{GLU}{THR}{VAL}
{ASP}{ALA}{LEU}
DescriptionThe native peptide Autocamtide 2 (KKALRRQETVDAL) is a highly selective substrate for Ca2+/calmodulin-dependent protein kinase (CaMK). The peptide Autocamtide 2 contains the sequence around the autophosphorylation site in the autoinhibitory domain of calmodulin-dependent protein kinase II (CaM kinase II). The fluorescent and biotinylated peptides are used to design assays for CaMKs.
SolubilitySoluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
FormulaC65H118N22O20
M.W.1527.77
Cas129198-88-5
Purity> 95%
StorageStore at -20°C
NotesHighly selective substrate for CaM kinase used for Ca2+/Calmodulin-dependent Protein Kinase studies.
* For Non-Clinical Research Use Only *


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 Peptide Libraries: GenScript has developed a rapid high-throughput parallel peptide synthesis platform, providing custom libraries of unbound peptides of 5-20 mer at very competitive prices.




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