| Cat. No. |
Size |
Price |
Figures |
|---|
RP10271-1 mg
| 1 mg | $ 47.50 | HPLC: 20060721145615 (PDF)
MS: 20060721145554 (PDF)
MSDS: 20080630235606 (PDF)
References:
- Ishida A, et al. Critical amino acid residues of AIP, a highly specific inhibitory peptide of calmodulin-dependent protein kinase II. FEBS Lett. May 1998; 427(1): 115-118.
- Tatone C, et al. Possible role for Ca(2+) calmodulin-dependent protein kinase II as an effector of the fertilization Ca(2+) signal in mouse oocyte activation. Mol. Hum. Reprod. Aug 2002; 8(8): 750-757.
- Aromolaran AA, Blatter LA. Modulation of intracellular Ca2+ release and capacitative Ca2+ entry by CaMKII inhibitors in bovine vascular endothelial cells. Am. J. Physiol., Cell Physiol. Dec 2005; 289(6): C1426-C1436.
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| Full Name | |
| Alias |
Autocamtide2; AC-2; AC2 |
Sequence
(one-letter code) |
KKALRRQETVDAL |
Sequence
(three-letter code) | {LYS}{LYS}{ALA}{LEU}{ARG}{ARG}{GLN}{GLU}{THR}{VAL}
{ASP}{ALA}{LEU} |
|---|
| Description | The native peptide Autocamtide 2 (KKALRRQETVDAL) is a highly selective substrate for Ca2+/calmodulin-dependent protein kinase (CaMK). The peptide Autocamtide 2 contains the sequence around the autophosphorylation site in the autoinhibitory domain of calmodulin-dependent protein kinase II (CaM kinase II). The fluorescent and biotinylated peptides are used to design assays for CaMKs. |
|---|
| Solubility | Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. |
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| Formula | C65H118N22O20 |
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| M.W. | 1527.77 |
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| Cas | 129198-88-5 |
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| Purity | > 95% |
|---|
| Storage | Store at -20°C |
| Notes | Highly selective substrate for CaM kinase used for Ca2+/Calmodulin-dependent Protein Kinase studies. |
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