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CKS-17

Cat. No. Size Price Figures
RP10281-0.5 mg
 		0.5 mg
$ 42.75
HPLC:  20060721145615  (PDF)
MS:  20060721145554  (PDF)
MSDS:  20080923210352  (PDF)


References:
  • Takahashi A, et al. A retroviral-derived immunosuppressive peptide activates mitogen-activated protein kinases. J. Immunol. Jun 2001; 166(11): 6771-6775.
  • Luangwedchakarn V, et al. A retroviral-derived peptide phosphorylates protein kinase D/protein kinase Cmu involving phospholipase C and protein kinase C. Peptides. May 2003; 24(5): 631-637.
  • Fan T, et al. The phosphorylation of phospholipase C-gamma1, Raf-1, MEK, and ERK1/2 induced by a conserved retroviral peptide. Peptides. Nov 2005; 26(11): 2165-2174.
Full Name
CKS-17
Alias CKS17
Sequence
(one-letter code)		 LQNRRGLDLLFLKEGGL
Sequence
(three-letter code)		{LEU}{GLN}{ASN}{ARG}{ARG}{GLY}{LEU}{ASP}{LEU}{LEU}
{PHE}{LEU}{LYS}{GLU}{GLY}{GLY}{LEU}
DescriptionThis peptide CKS-17 is considered as the major immunosuppressive site of retroviral TM protein. It can suppress T effector cell function in vitro. It has been shown that CKS-17 causes an imbalance of human types 1 and 2 cytokines and inhibition of the immune responses of lymphocytes, monocytes, and macrophages. CKS-17 induced increased intracellular levels of cAMP, which plays an important role in regulation of cytokine biosynthesis.
FormulaC87H148N26O24
M.W.1942.3
Purity> 95%
StorageStore at -20°C
* For Non-Clinical Research Use Only *




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