GenScript Catalog Peptide: PACAP (1-38), human, ovine, rat (RP10335)

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PACAP (1-38), human, ovine, rat

Cat. No.

Size

Price

Figures

RP10335-0.5 mg

0.5 mg

$ 142.50

MSDS: 20080713212741 (PDF)

References:

Yaka R, et al. Pituitary adenylate cyclase-activating polypeptide (PACAP(1-38)) enhances N-methyl-D-aspartate receptor function and brain-derived neurotrophic factor expression via RACK1. J. Biol. Chem. Mar 2003; 278(11): 9630-9638.
Tornoe K, et al. PACAP 1-38 as neurotransmitter in the porcine antrum. Regul. Pept. Sep 2001; 101(1-3): 109-121.
Tornoe K, et al. PACAP-(1-38) as neurotransmitter in the porcine adrenal glands. Am. J. Physiol. Endocrinol. Metab. Dec 2000; 279(6): E1413-1425.

RP10335-5 mg

5 mg

$ 950.00

Full Name

PACAP (1-38), human, ovine, rat

Sequence
(one-letter code)

HSDGIFTDSYSRYRKQMAVKKYLAAVLGKRYKQRVKNK-NH₂

Sequence
(three-letter code)

{HIS}{SER}{ASP}{GLY}{ILE}{PHE}{THR}{ASP}{SER}{TYR}
{SER}{ARG}{TYR}{ARG}{LYS}{GLN}{MET}{ALA}{VAL}{LYS}
{LYS}{TYR}{LEU}{ALA}{ALA}{VAL}{LEU}{GLY}{LYS}{ARG}
{TYR}{LYS}{GLN}{ARG}{VAL}{LYS}{ASN}{LYS}-NH₂

C-Terminal

NH₂

Description

PACAP (1-38), a novel neuropeptide isolated from the bovine hypothalamus is more active than vasoactive intestinal peptide (VIP) in stimulating adenylate cyclase (EC50=7 nM). PACAP 1-38 (10^-9 M) increased substance P (SP), gastrin releasing peptide (GRP), and VIP release. PACAP 1-38 (10^-8 M) inhibited gastrin secretion and stimulated somatostatin secretion and motility dose-dependently.

Solubility

The peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.

Formula

C₂₀₃H₃₃₁N₆₃O₅₃S₁

M.W.

4534.26

Cas

137061-48-4

Purity

> 95%

Storage

Store the peptide at -20°C.

Notes

PACAP stimulates adenylate cyclase in rat anterior pituitary cells.

* For Non-Clinical Research Use Only *

Precast Gels

Code	Name	Size	Price
RP10334	peptide : PACAP (1-27), human, ovine, rat	0.5 mg	$ 104.50
RP10334	peptide : PACAP (1-27), human, ovine, rat	5 mg	$ 722.00
RP10337	peptide : PACAP (6-27), human, ovine, rat	0.5 mg	$ 80.75
RP10338	peptide : PACAP (6-38), human, ovine, rat	0.5 mg	$ 133.00
RP10338	peptide : PACAP (6-38), human, ovine, rat	5 mg	$ 950.00
RP10339	peptide : PACAP 38, frog	0.5 mg	$ 161.50
RP10339	peptide : PACAP 38, frog	5 mg	$ 1026.00
RP10341	peptide : PACAP-Related Peptide (PRP), human	0.5 mg	$ 137.75
RP10342	peptide : PACAP-Related Peptide (PRP), rat	0.5 mg	$ 118.75

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