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Orexin B, rat, mouse

Cat. No. Size Price Figures
RP10416-0.5 mg
 		0.5 mg
$ 90.00
MSDS:  20080714020118  (PDF)

EXAMPLE:
Orexin B, rat, mouse Example
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References:
  • Haj-Dahmane S, Shen RY. The wake-promoting peptide orexin-B inhibits glutamatergic transmission to dorsal raphe nucleus serotonin neurons through retrograde endocannabinoid signaling. J. Neurosci. Jan 2005; 25(4): 896-905.
  • Grudt TJ, et al. Hypocretin-2 (orexin-B) modulation of superficial dorsal horn activity in rat. J. Physiol. Jan 2002; 538(Pt2):517-525.
Full Name
Orexin B, rat, mouse
Sequence
(one-letter code)		 RPGPPGLQGRLQRLLQANGNHAAGILTM-NH2
Sequence
(three-letter code)		{ARG}{PRO}{GLY}{PRO}{PRO}{GLY}{LEU}{GLN}{GLY}{ARG}
{LEU}{GLN}{ARG}{LEU}{LEU}{GLN}{ALA}{ASN}{GLY}{ASN}
{HIS}{ALA}{ALA}{GLY}{ILE}{LEU}{THR}{MET}-NH2
C-TerminalNH2
DescriptionOrexin B is a hypothalamatic neuropeptide stimulating food intake in rats. Orexin B activates OX2 receptors. Both OX1 and OX2 receptors are involved in maintaining arousal. OX2 receptors appear to be inhibitory autoreceptors on orexin-containing neurons. Orexin B stimulates food consumption in a similar manner to orexin A, but the effect did not last as long as that of orexin A. The affinity of orexin B for the OX1 receptor is significantly lower than that of orexin A. Binding affinities for the OX2 receptor are similar for orexin A and B.
SolubilitySoluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
FormulaC126H215N45O34S
M.W.2936.4
Purity> 95%
StorageStore at -20°C.
* For Non-Clinical Research Use Only *
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RP10415peptide : Orexin B, human0.5 mg
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RP10414 peptide : Orexin B, canine0.5 mg
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