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Neuropeptide Y (13-36), human

Cat. No. Size Price Figures
RP10488-0.5 mg
0.5 mg
$ 57.00
HPLC:  20060721145617  (PDF)
MS:  20060721145556  (PDF)
MSDS:  20080813222219  (PDF)


References:
  • Schwippert WW, et al. Neuropeptide Y (NPY) or fragment NPY 13-36, but not NPY 18-36, inhibit retinotectal transfer in cane toads Bufo marinus. Neurosci. Lett. Aug 1998; 253(1): 33-36.
  • Aguirre JA, et al. Increased vasopressor actions of intraventricular neuropeptide Y-(13-36) in spontaneously hypertensive versus normotensive Wistar-Kyoto rats. Possible relationship to increases in Y2 receptor binding in the nucleus tractus solitarius. Brain Res. Jul 1995; 684(2): 159-164.
  • Amlal H, et al. Estrogen up-regulates neuropeptide Y Y1 receptor expression in a human breast cancer cell line. Cancer Res. Apr 2006; 66(7): 3706-3714.
RP10488-5 mg
5 mg
$ 380.00
Full Name
Neuropeptide Y (13-36), human
Alias NPY 13-36
Sequence
(one-letter code)
PAEDMARYYSALRHYINLITRQRYNH2
Sequence
(three-letter code)
{PRO}{ALA}{GLU}{ASP}{MET}{ALA}{ARG}{TYR}{TYR}{SER}
{ALA}{LEU}{ARG}{HIS}{TYR}{ILE}{ASN}{LEU}{ILE}{THR}
{ARG}{GLN}{ARG}{TYR}-NH2
C-TerminalNH2
DescriptionThe C-terminal NPY fragment (13-36) [NPY-(13-36)], a Y2 receptor agonist, elicits vasopressor responses upon central administration. The cardiovascular responses of NPY-(13-36), together with the distribution of NPY receptor subtypes within the nucleus tractus solitarius (nTS), have been studied in spontaneously hypertensive rats (SHR). Neuropeptide Y (13-36) (NPY 13-36) stimulates both Y2 and Y5 NPY receptor subtypes, but causes no increase in food intake even when injected at high doses, while the full-length NPY is one of the most potent physiological stimulants of feeding yet described. NPY 13-16 inhibits retinotectal transfer in amphibians.
FormulaC134H207N41O36S1
M.W.3000.41
Purity> 95%
StorageStore the peptide at -20°C.
* For Non-Clinical Research Use Only *
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