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Neurokinin B

Cat. No. Size Price Figures
RP10517-1 mg
1 mg
$ 47.50
HPLC:  20060721145617  (PDF)
MS:  20060721145557  (PDF)
MSDS:  20080924023011  (PDF)

STRUCTURE:
Neurokinin B Structure
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References:
  • Duarte CR, et al. Incongruent pattern of neurokinin B expression in rat and mouse brains. Cell Tissue Res. Jan 2006; 323(1): 43-51.
  • Cuadrado I, et al. Mapping of neurokinin b in the cat brainstem. Anat. Embryol. (Berl). Sep 2005; 210(2): 133-143.
  • Krajewski SJ, et al. Morphologic evidence that neurokinin B modulates gonadotropin-releasing hormone secretion via neurokinin 3 receptors in the rat median eminence. J. Comp. Neurol. Aug 2005; 489(3): 372-386.
Full Name
Neurokinin B
Alias NKB
Sequence
(one-letter code)
DMHDFFVGLM-NH2
Sequence
(three-letter code)
{ASP}{MET}{HIS}{ASP}{PHE}{PHE}{VAL}{GLY}{LEU}{MET}-NH2
C-TerminalNH2
DescriptionNeurokinin B belongs to the tachykinin family. Neurokinin B may play an important role in the olfactory, gustatory, visceral, and neuroendocrine processing information. Neurokinin B is potent bronchioconstrictor and has neruomodulatory roles in various brain functions. Neurokinin B is a member of the tachykinin family of neuropeptides that also includes Substance P and Neurokinin A. These carboxyl terminal-amidated peptides are derived from two preprotachykinin genes - the PPT-A gene encodes the sequences of Substance P, Neurokinin A, and neuropeptide K and the PPT-B gene encodes the sequence of Neurokinin B. Neurokinin B stimulate the production of immunoglobulins in peripheral B lymphocytes, This conditional response to Neurokinin B is likely due NK-3 receptors present only following co-culture and activation.
SolubilitySoluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
FormulaC55H79N13O14S2
M.W.1210.42
Cas86933-75-7
Purity> 95%
StorageStore at -20°C.
NotesNovel mammalian Tachykinin in Porcine spinal cord.
* For Non-Clinical Research Use Only *
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