| Cat. No. |
Size |
Price |
Figures |
|---|
RP10553-5 mg
| 5 mg | $ 23.75 | MSDS: 20080924032815 (PDF)
References:
- Korf J, et al. Automated precolumn fluorescence labelling by carbodiimide activation of N-acetylaspartate and N-acetylaspartylglutamate applied to an HPLC brain tissue analysis. Anal. Biochem. Aug 1991; 196(2): 350-355.
- Ffrench-Mullen JM, et al. N-Acetylaspartylglutamate: possible role as the neurotransmitter of the lateral olfactory tract. Proc. Natl. Acad Sci. U S A. Jun 1985; 82(11): 3897-3900.
- Zaczek R, et al. N-acetylaspartylglutamate: an endogenous peptide with high affinity for a brain 'glutamate' receptor. Proc. Natl. Acad Sci. U S A. Feb 1983; 80(4): 1116-1119.
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| Full Name | |
| Alias |
N-Acetylaspartylglutamate , NAAG |
Sequence
(one-letter code) |
DE |
Sequence
(three-letter code) | AC-{ASP}{GLU} |
|---|
| Description | Ac-Asp-Glu (N-Acetylaspartylglutamate, NAAG) is an endogeneous peptide with high affinity for a brain Glutamate receptor. Also Ac-Asp-Glu is the most abundant peptide neurotransmitter in the mammalian central nervous system. One role for Ac-Asp-Glu following synaptic release is the activation of metabotropic autoreceptors that inhibit subsequent transmitter release. A second role is the production of extracellular glutamate following Ac-Asp-Glu hydrolysis. High concentrations of Ac-Asp-Glu selectively activate NMDA receptors on mouse spinal cord neurons in cell culture.
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| Solubility | Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. |
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| Formula | C11H16N2O8 |
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| M.W. | 304.25 |
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| Purity | > 95% |
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| Storage | Before using, store the peptide in the DRY form at 0 - 5°C. For best and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions. |
| N-Terminal | AC |
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