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β-Melanocyte Stimulating Hormone (MSH), human  |
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| Cat. No. |
Size |
Price |
Figures |
RP10648-1 mg
| 1 mg | $ 90.25 | HPLC: 20060721145618 (PDF) MS: 20060721145558 (PDF) MSDS: 20080822042047 (PDF)
References:
- Hinney A, et al. Prevalence, spectrum, and functional characterization of melanocortin-4 receptor gene mutations in a representative population-based sample and obese adults from Germany. J.Clin.Endocrinol.Metab. May 2006; 91(5): 1761-1769.
- Leder EH, Silverstein JT. The pro-opiomelanocortin genes in rainbow trout (Oncorhynchus mykiss): duplications, splice variants, and differential expression. J.Endocrinol. Feb 2006; 188(2): 355-363.
- Spencer JD, et al. A novel mechanism in control of human pigmentation by {beta}-melanocyte-stimulating hormone and 7-tetrahydrobiopterin. J.Endocrinol. Nov 2005; 187(2): 293-302.
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| Full Name | | β-Melanocyte Stimulating Hormone (MSH), human |
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| Alias |
beta melanocyte stimulating hormone, β-MSH; βMSH; b-MSH, bMSH; beta-MSH; betaMSH |
Sequence (one-letter code) |
AEKKDEGPYRMEHFRWGSPPKD | Sequence (three-letter code) | {ALA}{GLU}{LYS}{LYS}{ASP}{GLU}{GLY}{PRO}{TYR}{ARG} {MET}{GLU}{HIS}{PHE}{ARG}{TRP}{GLY}{SER}{PRO}{PRO} {LYS}{ASP} | | Description | Alpha-MSH (melanocyte stimulating hormone) has generally been assumed to be the endogenous ligand acting at the melanocortin-4 receptor (MC4-R), activation of which in the hypothalamus leads to reduced feeding. However, beta-MSH is also capable of activating MC4-R and inhibiting feeding. The researchers found that obese children are more likely to carry a rare variant of so-called beta-melanocyte-stimulating hormone (beta-MSH) than children of normal weight. |
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| Formula | C118H174N34O35S1 | | M.W. | 2661 | | Cas | 17908-57-5 |
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| Purity | > 95% | | Storage | Store the peptide at -20°C. Keep container tightly closed. Store in a cool dry place. |
| * For Non-Clinical Research Use Only *
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