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β-Melanocyte Stimulating Hormone (MSH), human

Cat. No. Size Price Figures
RP10648-1 mg
 		1 mg
$ 90.25
HPLC:  20060721145618  (PDF)
MS:  20060721145558  (PDF)
MSDS:  20080822042047  (PDF)


References:
  • Hinney A, et al. Prevalence, spectrum, and functional characterization of melanocortin-4 receptor gene mutations in a representative population-based sample and obese adults from Germany. J.Clin.Endocrinol.Metab. May 2006; 91(5): 1761-1769.
  • Leder EH, Silverstein JT. The pro-opiomelanocortin genes in rainbow trout (Oncorhynchus mykiss): duplications, splice variants, and differential expression. J.Endocrinol. Feb 2006; 188(2): 355-363.
  • Spencer JD, et al. A novel mechanism in control of human pigmentation by {beta}-melanocyte-stimulating hormone and 7-tetrahydrobiopterin. J.Endocrinol. Nov 2005; 187(2): 293-302.
Full Name
β-Melanocyte Stimulating Hormone (MSH), human
Alias beta melanocyte stimulating hormone, β-MSH; βMSH; b-MSH, bMSH; beta-MSH; betaMSH
Sequence
(one-letter code)		 AEKKDEGPYRMEHFRWGSPPKD
Sequence
(three-letter code)		{ALA}{GLU}{LYS}{LYS}{ASP}{GLU}{GLY}{PRO}{TYR}{ARG}
{MET}{GLU}{HIS}{PHE}{ARG}{TRP}{GLY}{SER}{PRO}{PRO}
{LYS}{ASP}
DescriptionAlpha-MSH (melanocyte stimulating hormone) has generally been assumed to be the endogenous ligand acting at the melanocortin-4 receptor (MC4-R), activation of which in the hypothalamus leads to reduced feeding. However, beta-MSH is also capable of activating MC4-R and inhibiting feeding. The researchers found that obese children are more likely to carry a rare variant of so-called beta-melanocyte-stimulating hormone (beta-MSH) than children of normal weight.
FormulaC118H174N34O35S1
M.W.2661
Cas17908-57-5
Purity> 95%
StorageStore the peptide at -20°C. Keep container tightly closed. Store in a cool dry place.
* For Non-Clinical Research Use Only *
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