| Cat. No. |
Size |
Price |
Figures |
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RP10650-1 mg
| 1 mg | $ 52.25 | MSDS: 20080820232721 (PDF)
References:
- Harmer SC, Bicknell AB. Role of gamma-MSH peptides in the regulation of adrenal steroidogenesis. Peptides. Oct 2005; 26(10): 1944-1951.
- Mayorov AV, et al. Development of cyclic gamma-MSH analogues with selective hMC3R agonist and hMC3R/hMC5R antagonist activities. J. Med. Chem. Mar 2006; 49(6): 1946-1952.
- Cai M, et al. Novel 3D pharmacophore of alpha-MSH/gamma-MSH hybrids leads to selective human MC1R and MC3R analogues. J. Med. Chem. Mar 2005; 48(6): 1839-1848.
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| Full Name | | γ-1-Melanocyte Stimulating Hormone (MSH), amide |
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| Alias |
γ1-MSH; g-1-MSH; g1-MSH; gamma-1-MSH; gamma1-MSH, γ-1-Melanocyte Stimulating Hormone; γ1-Melanocyte Stimulating Hormone; g-1-Melanocyte Stimulating Hormone; g1-Melanocyte Stimulating Hormone; gamma-1-Melanocyte Stimulating Hormone; gamma1-Melanocyte Stimulating Hormone |
Sequence
(one-letter code) |
YVMGHFRWDRF-NH2 |
Sequence
(three-letter code) | {TYR}{VAL}{MET}{GLY}{HIS}{PHE}{ARG}{TRP}{ASP}{ARG}
{PHE}-NH2 |
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| C-Terminal | NH2 |
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| Description | Gamma-MSH (Melanocyte Stimulating Hormone), a putative hormone in the N-terminal region of the ACTH/beta- endorphin (beta-EP) precursor protein, was studied by RIA with an antiserum against gamma 3-MSH in ACTH-producing mouse pituitary tumor cells, AtT-20/D16v. Gamma-MSH peptides have low intrinsic melanotropic activity in mammalian melanoma cells; the specific pigmentary responses appear to be affected by the structure of the C-terminal portion.
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| Formula | C72H97N21O14S1 |
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| M.W. | 1512.9 |
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| Purity | > 95% |
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| Storage | Store the peptide at -20°C. Keep container tightly closed. |
| Notes | Gamma-1-MSH is derived from ACTH 1-13. Gamma-1-MSH is a hormone that stimulates melanogenesis and facilitates learning and memory. Gamma-1-MSH can affect inflammatory and immune responses and peripheral nerve regeneration. |
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