GenScript Catalog Peptide: [Nle<sup>4</sup>, D-Phe<sup>7</sup>]-α-Melanocyte Stimulating Hormone (MSH), amide (RP10658)

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[Nle⁴, D-Phe⁷]-α-Melanocyte Stimulating Hormone (MSH), amide

Cat. No.

Size

Price

Figures

RP10658-1 mg

1 mg

$ 66.50

HPLC:  20080805043453  (PDF)
MS:  20080805043915  (PDF)
MSDS:  20080821020004  (PDF)

References:

Cragnolini AB, et al. Anxiety-like behavior induced by IL-1beta is modulated by alpha-MSH through central melanocortin-4 receptors. Peptides. Jun 2006; 27(6): 1451-1456.
Yamaoka-Tojo M, et al. Central neurotranspeptide, alpha-melanocyte-stimulating hormone (alpha-MSH) is upregulated in patients with congestive heart failure. Intern. Med. Jul 2006; 45(7): 429-434.

RP10658-5 mg

5 mg

$ 266.00

Full Name

[Nle⁴, D-Phe⁷]-α-Melanocyte Stimulating Hormone (MSH), amide

Alias

αMSH; a-MSH; aMSH; alpha-MSH; alphaMSH;α-Melanocyte Stimulating Hormone; αMelanocyte Stimulating Hormone; a-Melanocyte Stimulating Hormone; aMelanocyte Stimulating Hormone; alpha-Melanocyte Stimulating Hormone; alphaMelanocyte Stimulating Hormone, NDP-MSH

Sequence
(one-letter code)

Ac-SYSNleEHfRWGKPV-NH₂

Sequence
(three-letter code)

Ac-{SER}{TYR}{SER}{NLE}{GLU}{HIS}{d-PHE}{ARG}{TRP}{GLY}
{LYS}{PRO}{VAL}-NH₂

C-Terminal

NH₂

Description

[Nle4, DPhe7]-alpha-MSH (NDP-MSH), a highly potent analogue of alpha-melanocyte-stimulating hormone (alpha-MSH), possesses nanomolar efficacies at all the melanocortin receptor subtypes except the MC2R. Evaluation of the melanocortin 'message' sequence of [Nle4, DPhe7]-alpha-MSH was performed on the human melanocortin receptor subtypes designated hMC1, hMC3R, hMC4R, and hMC5R.

Formula

C₇₈H₁₁₁N₂₁O₁₉

M.W.

1647

Cas

75921-69-6

Purity

> 95%

Storage

Store at -20°C. Keep tightly closed. Store in a cool dry place.

N-Terminal

Notes

[Nle4,DPhe7] alpha-MSH is a hormone that stimulates melanogenesis and facilitates learning and memory. [Nle4,DPhe7] alpha-MSH can affect inflammatory and immune responses and peripheral nerve regeneration.

* For Non-Clinical Research Use Only *

Precast Gels

Code	Name	Size	Price
RP10644	peptide : α-Melanocyte-Stimulating Hormone (MSH), amide	1 mg	$ 23.75
RP10644	peptide : α-Melanocyte-Stimulating Hormone (MSH), amide	5 mg	$ 57.00
RP10648	peptide : β-Melanocyte Stimulating Hormone (MSH), human	1 mg	$ 90.25
RP10650	peptide : γ-1-Melanocyte Stimulating Hormone (MSH), amide	1 mg	$ 52.25
RP17323	peptide : Melanotan (MT)-II	5 mg	$ 82.50
RP17325	peptide : γ-3-Melanocyte-Stimulating Hormone (MSH)	1 mg	$ 165.00

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