GenScript Catalog Peptide: Leucokinin I (RP10692)

Gauthier SA, Hewes RS. Transcriptional regulation of neuropeptide and peptide hormone expression by the Drosophila dimmed and cryptocephal genes. J.Exp.Biol. May 2006; 209(10): 1803-1815.
Linton SM, O'Donnell MJ. Novel aspects of the transport of organic anions by the malpighian tubules of Drosophila melanogaster. J.Exp.Biol. Dec 2000; 203(23): 3575-3584.
Radford JC, et al. Functional characterisation of the Anopheles leucokinins and their cognate G-protein coupled receptor. J.Exp.Biol. Dec 2004; 207(26): 4573-4586.

Full Name

Leucokinin I

Alias

LeucokininI; Leucokinin 1; Leucokinin1

Sequence
(one-letter code)

DPAFNSWG-NH₂

Sequence
(three-letter code)

{ASP}{PRO}{ALA}{PHE}{ASN}{SER}{TRP}{GLY}-NH₂

C-Terminal

NH₂

Description

Leucokinin I is similar to those identified in two other mosquito species, Aedes aegypti and Culex salinarius. Additionally, Anopheles leucokinin I displays sequence similarity to Drosophila melanogaster leucokinin. Using a combination of computational and molecular approaches, a full-length cDNA for a candidate leucokinin-like receptor was isolated from A. stephensi, a close relative of A. gambiae. Alignment of the known leucokinin receptors--all G protein-coupled receptors (GPCRs)--with this receptor, identified some key conserved regions within the receptors, notably transmembrane (TM) domains I, II, III, VI and VII.

Solubility

Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.

Formula

C₄₁H₅₃N₁₁O₁₂

M.W.

892

Purity

> 95%

Storage

Before using, store the peptide (Leucokinin I) in the DRY form at 0 - 5�C. For best and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions.

* For Non-Clinical Research Use Only *


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