GenScript Catalog Peptide: Leucokinin VIII (RP10698)

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Leucokinin VIII

Cat. No.

Size

Price

Figures

RP10698-1 mg

1 mg

$ 23.75

HPLC:  20060721145618  (PDF)
MS:  20060721145558  (PDF)
MSDS:  20080821215202  (PDF)

References:

Yu MJ, Beyenbach KW. Effects of leucokinin-VIII on Aedes Malpighian tubule segments lacking stellate cells. J.Exp.Biol. Jan 2004; 207(3): 519-526.
Yu MJ, Beyenbach KW. Leucokinin activates Ca(2+)-dependent signal pathway in principal cells of Aedes aegypti Malpighian tubules. Am.J.Physiol.Renal.Physiol. Sep 2002; 283(3): 499-508.
Wang S, et al. Leucokinin increases paracellular permeability in insect Malpighian tubules. J.Exp.Biol. May 1996; 199(11): 2537-2542.

Full Name

Leucokinin VIII

Alias

LeucokininVIII; Leucokinin 8; Leucokinin8

Sequence
(one-letter code)

GASFYSWG-NH₂

Sequence
(three-letter code)

{GLY}{ALA}{SER}{PHE}{TYR}{SER}{TRP}{GLY}-NH₂

C-Terminal

NH₂

Description

The effects of leucokinin-VIII were qualitatively and quantitatively similar in six tubule segments containing no stellate cells; V(t) decreased from 37.8+/-7.0 mV to 3.4+/-0.6 mV, R(t) decreased from 8.8+/-2.1 kOmegacm to 1.7+/-0.2 kOmegacm, and DP(Cl) increased from 5.8+/-2.6 mV to 50.0+/-2.1 mV. Thus, stellate cells are not required for signaling or mediating the effects of leucokinin in Malpighian tubules of Aedes aegypti. The results further support previous observations that principal cells signal the effects of leucokinin-VIII to increase the Cl(-) conductance of the paracellular pathway through septate (or tight) junctions.

Formula

C₄₂H₅₂N₁₀O₁₁

M.W.

872.9

Purity

> 95%

Storage

Store at -20°C.

* For Non-Clinical Research Use Only *

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