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Leptin (22-56), human  |
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| Cat. No. |
Size |
Price |
Figures |
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RP10702-0.5 mg
| 0.5 mg | $ 142.50 | HPLC: 20060721145618 (PDF)
MS: 20060721145558 (PDF)
MSDS: 20080703225100 (PDF)
References:
- Markowska A, et al. Leptin and leptin receptor expression in the myometrium and uterine myomas: Is leptin involved in tumor development? Int. J. Oncol. Dec 2005; 27(6): 1505-1509.
- Malendowicz LK, et al. Acute in vivo effects of leptin and leptin fragments on corticosteroid hormone secretion and entero-insular axis in the rat. Int.. J Mol. Med. Jun 2004; 13(6): 829-834.
- Stamatiadis DN, et al. Elevated leptin fragments in renal failure correlate with BMI and haematopoiesis and are normalized by haemodialysis. Clin. Endocrinol. (Oxf). Apr 2004; 60(4): 434-441.
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| Full Name | |
Sequence
(one-letter code) |
VPIQKVQDDTKTLIKTIVTRINDISHTQSVSSKQK | Sequence
(three-letter code) | {VAL}{PRO}{ILE}{GLN}{LYS}{VAL}{GLN}{ASP}{ASP}{THR}
{LYS}{THR}{LEU}{ILE}{LYS}{THR}{ILE}{VAL}{THR}{ARG}
{ILE}{ASN}{ASP}{ILE}{SER}{HIS}{THR}{GLN}{SER}{VAL}
{SER}{SER}{LYS}{GLN}{LYS} |
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| Description | Leptin (22-56), a biological active fragment of Leptin, may have important physiological significance for the anorexia, hypogonadism, and anaemia commonly seen in HD patients. Leptin (22-56), at concentrations of 10(-7) and 10(-6) M, enhance the proliferative activity of both the normal myometrium and myoma cells in primary culture. |
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| Solubility | Insoluble in water. Dissolve peptide with small amount of 60% Acetonitrile with 0.1% TFA solution - followed with water or desired buffer. |
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| Formula | C171H298N50O56 |
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| M.W. | 3950.52 |
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| Purity | > 95% |
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| Storage | Store at -20°C | | Notes | ICV injection (500 ng) reduces food intake in rats. |
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| * For Non-Clinical Research Use Only *
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