| Cat. No. |
Size |
Price |
Figures |
RP10773-0.5 mg
| 0.5 mg | $ 90.25 | MSDS: 20080728215426 (PDF)
References:
- Creutzfeldt WO, et al. Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients. Diabetes Care. Jun 1996; 19(6): 580-586.
- Jia X, et al. Effects of glucose-dependent insulinotropic polypeptide and glucagon-like peptide-I-(7-36) on insulin secretion. Am. J. Physiol. Apr 1995; 268(4 Pt 1): E645-E651.
- Richter G, et al. Characterization of glucagon-like peptide-I(7-36)amide receptors of rat lung membranes by covalent cross-linking. FEBS. Lett. Mar 1991; 280(2): 247-250.
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| Full Name | | Glucagon-Like Peptide (GLP) I (7-36), amide, human |
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| Alias |
GLP-1 (7-36), amide, human, Glucagon Like PeptideI; Glucagon Like Peptide 1; Glucagon Like Peptide1; GLP-I; GLPI; GLP-1; GLP1 |
Sequence (one-letter code) |
HAEGTFTSDVSSYLEGQAAKEFIAWLVKGR-NH2 |
Sequence (three-letter code) | {HIS}{ALA}{GLU}{GLY}{THR}{PHE}{THR}{SER}{ASP}{VAL} {SER}{SER}{TYR}{LEU}{GLU}{GLY}{GLN}{ALA}{ALA}{LYS} {GLU}{PHE}{ILE}{ALA}{TRP}{LEU}{VAL}{LYS}{GLY}{ARG}-NH2 |
| C-Terminal | NH2 |
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| Description | Glucagon-Like Peptide I (7-36) (GLP)-1 (7-36)-NH2 is a peptide found in the mucosal endocrine cells of the intestine, and plasma levels of Glucagon-Like Peptide I (7-36)-NH2 immunoreactivity show a rise after the ingestion of a fat or mixed-component meal. The effects of physiological infusion of Glucagon-Like Peptide I (7-36)-NH2 on a submaximal gastric acid secretion in healthy volunteers at a rate known to mimic the observed postprandial rise in plasma concentrations. Some results suggest a novel role for Glucagon-Like Peptide I (7-36)-NH2 as a physiological inhibitor of gastric acid secretion in humans. |
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| Solubility | Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents. |
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| Formula | C149H226N40O45 |
| M.W. | 3297.5 |
| Cas | 107444-51-9 |
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| Purity | > 95% |
| Storage | Store at -20°C. Keep tightly closed. Store in a cool dry place. |