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Galantide

Cat. No. Size Price Figures
RP10804-0.5 mg
0.5 mg
$ 71.25
MSDS:  20080630212733  (PDF)


References:
  • Korolkiewicz RP, et al. Mechanism of the contractile effects of galantide and Galanin(1-14) [alpha-aminobutyric acid]scyliorhinin-I in rat isolated fundus strips. Med. Sci. Monit. Jan 2002; 8(1): BR19-BR23.
  • Bivalacqua TJ, et al. Nitric oxide-mediated erectile effects of galantide but not galanin in vivo. Nitric. Oxide. Apr 2000; 4(2): 94-102.
Full Name
Galantide
Sequence
(one-letter code)
GWTLNSAGYLLGPQQFFGLM-NH2
Sequence
(three-letter code)
{GLY}{TRP}{THR}{LEU}{ASN}{SER}{ALA}{GLY}{TYR}{LEU}
{LEU}{GLY}{PRO}{GLN}{GLN}{PHE}{PHE}{GLY}{LEU}{MET}
C-TerminalNH2
DescriptionThe galanin-antagonist galantide, a chimeric peptide obtained from amino acids 1-13 of galanin attached to the C-terminal fragment of bradykinin, has been found to improve social memory in 'social recognition' test when i.c.v. administered at doses varying from 6-6000nmoles. Galantide causes widespread antagonism to the action of galanin and reversibly blocks the neuronal actions of galanin in a dose-dependent manner. It inhibits the release of acetylcholine, reduces the response to galanin in the hypothalamus, and blocks the effect of galanin on glucose-induced insulin secretion.
SolubilitySoluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
FormulaC104H151N25O26S1
M.W.2199.6
Cas138579-66-5
Purity> 95%
Storagestore at -20°C. Keep tightly closed. Store in a cool dry place.
* For Non-Clinical Research Use Only *
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