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Fibrinolysis Inhibiting Factor

Cat. No. Size Price Figures
RP10834-1 mg
1 mg
$ 24.00
MSDS:  20080117042843  (DOC)
MSDS:  20080117042953  (PDF)


References:
  • Boffa MB, et al. A role for CCAAT/enhancer-binding protein in hepatic expression of thrombin-activable fibrinolysis inhibitor. J. Biol. Chem. Jul 2002; 277(28): 25329-25336.
  • Bajzar L, et al. Both cellular and soluble forms of thrombomodulin inhibit fibrinolysis by potentiating the activation of thrombin-activable fibrinolysis inhibitor. J Biol Chem. Jan 1998; 273(5): 2792-2798.
RP10834-5 mg
5 mg
$ 76.00
Full Name
Fibrinolysis Inhibiting Factor
Sequence
(one-letter code)
GPRP
Sequence
(three-letter code)
{GLY}{PRO}{ARG}{PRO}
DescriptionFibrinolysis inhibiting factor is a peptide that mimics the N terminus of the alpha chain of fibrin. It binds to the polymerization pocket in the alpha chain more tightly than a peptide corresponding to the chain native sequence GPRV. The complex between GPRP and fibrinogen causes an increased resistance to degradation by plasmin, and the polymerization reaction is depressed by the addition of excess peptide. Fibrin assembly and the acceleration of the factor XIIIa reaction can be prevented by this homologue of the natural sequence of amino acids.
FormulaC18H31N7O5
M.W.425.48
Purity> 95%
StorageStore the peptide at -20°C.
* For Non-Clinical Research Use Only *
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