| Cat. No. |
Size |
Price |
Figures |
|---|
RP10926-5 mg
| 5 mg | $ 42.75 | HPLC: 20060721145620 (PDF)
MS: 20060721145559 (PDF)
MSDS: 20080704052908 (PDF)
STRUCTURE:
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References:
- Mizoguchi H, et al. Possible Involvement of Dynorphin A-(1-17) Release via {micro}1-Opioid Receptors in Spinal Antinociception by Endomorphin-2. J. Pharmacol. Exp. Ther. Apr 2006; 317(1): 362-368.
- Botros M, et al. Endomorphin-1 and endomorphin-2 differentially interact with specific binding sites for substance P (SP) aminoterminal SP(1-7) in the rat spinal cord. Peptides. Apr 2006; 27(4):753-759.
- Viard E and Sapru HN, et al. Endomorphin-2 in the medial NTS attenuates the responses to baroreflex activation. Brain Res. Feb 2006; 1073-1074:365-373.
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| Full Name | |
| Alias |
Endomorphin2 |
Sequence
(one-letter code) |
YPFF-NH2 | Sequence
(three-letter code) | {TYR}{PRO}{PHE}{PHE}-NH2 |
|---|
| C-Terminal | NH2 |
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| Description | Endomorphin 2 is a potent, selective endogenous μ opioid receptor agonist. The physiological function of endomorphin-2 as a neurotransmitter or neuromodulator may cease through the rapid enzymatic process in the synapse of brain, as for other neuropeptides. Some results indicate that the administration of the endogenous μ-opioid ligand endomorphin-2, but not endomorphin-1, into the brain produces an antitussive effect via mainly naloxonazine-insensitive μ-opioid receptors, namely μ2-opioid receptors and partially kappa-opioid receptors. |
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| Solubility | Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. |
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| Formula | C32H37N5O5 |
|---|
| M.W. | 571.67 |
|---|
| Cas | 141801-26-5 |
|---|
| Purity | > 95% |
|---|
| Storage | Store at -20°C. Keep tightly closed. |
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