Peptide Products
You are here:  Products » Peptide Products » Catalog Peptides - Hot Products »  Calcitonin Gene Related Peptide (CGRP) (8-37), rat   
 
A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z  ALL  HotProducts  
Search by Catalog Number :(eg.RP01001)
Search by Name :(eg.Parathyroid Hormone (PTH))
Search by Sequence : (One letter code)
Search by Sequence : (Three letter code)

 
Calcitonin Gene Related Peptide (CGRP) (8-37), rat

Cat. No. Size Price Figures
RP11090-0.5 mg
 		0.5 mg
$ 90.25
HPLC:  20060721145620  (PDF)
MS:  20060721145600  (PDF)
MSDS:  20080813211304  (PDF)


References:
  • Kawase T, et al. Immature osteoblastic MG63 cells possess two calcitonin gene-related peptide receptor subtypes that respond differently to [Cys(Acm)(2,7)] calcitonin gene-related peptide and CGRP(8-37). Am. J. Physiol., Cell Physiol. Oct 2005; 289(4): C811-818.
  • Smith DD, et al. Modifications to the N-terminus but not the C-terminus of calcitonin gene-related peptide(8-37) produce antagonists with increased affinity. J. Med. Chem. Jun 2003; 46(12): 2427-2435.
  • Kaygisiz Z, et al. The effect of adrenomedullin, amylin fragment 8-37 and calcitonin gene-related peptide on contractile force, heart rate and coronary perfusion pressure in isolated rat hearts. Acta. Physiol. Hung. 2003; 90(2): 133-146.
Full Name
Calcitonin Gene Related Peptide (CGRP) (8-37), rat
Sequence
(one-letter code)		 VTHRLAGLLSRSGGVVKDNFVPTNVGSEAF-NH2
Sequence
(three-letter code)		{VAL}{THR}{HIS}{ARG}{LEU}{ALA}{GLY}{LEU}{LEU}{SER}
{ARG}{SER}{GLY}{GLY}{VAL}{VAL}{LYS}{ASP}{ASN}{PHE}
{VAL}{PRO}{THR}{ASN}{VAL}{GLY}{SER}{GLU}{ALA}{PHE}-NH2
C-TerminalNH2
DescriptionCalcitonin Gene Related Peptide (CGRP)(8-37) inhibits the evoked discharge frequency of wide dynamic range neurons in dorsal horn of the spinal cord in rats. The present study was performed to explore the effect of CGRP(8-37) on the electrical stimulation-evoked discharge frequency of wide dynamic range (WDR) neurons in the dorsal horn of the spinal cord in rats. The results indicate that CGRP receptors play an important role in the transmission of presumed nociceptive information in the dorsal horn of the spinal cord.
SolubilitySoluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
FormulaC138H224N42O41
M.W.3127.6
Purity> 95%
StorageBefore using, store the peptide in the DRY form at 0 - 5 °C. For best and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions.
Notesa potent, long-lasting vasodilator; activation of CGRP receptors on pancreatic β-cells increases plasma levels of pancreatic enzymes.
* For Non-Clinical Research Use Only *
Related Products:
CodeNameSizePrice 
RP11099peptide : Calcitonin, salmon0.5 mg
$ 57.00
RP11098 peptide : Calcitonin, rat0.5 mg
$ 71.25
RP11096peptide : Calcitonin, chicken0.5 mg
$ 71.25
RP11095 peptide : Calcitonin Gene Related Peptide (CGRP), rat0.5 mg
$ 128.25
RP11093peptide : Calcitonin Gene Related Peptide (CGRP), chicken0.5 mg
$ 118.75
RP11092 peptide : Calcitonin Gene Related Peptide (CGRP) II, rat0.5 mg
$ 118.75
RP11089peptide : Calcitonin Gene Related Peptide (CGRP) (8-37), human0.5 mg
$ 90.25
RP13606 peptide : Calcitonin (8-32), salmon0.2 mg
$ 137.75
GN068889ORF Clone : Calca10 ug
$ 483.75
GN068890 ORF Clone : Calca10 ug
$ 483.75




Our customer service is available 24 hours a day, Monday through Friday. You may contact us any time for assistance.