GenScript Catalog Peptide: C-Peptide (3-33), human (RP11116)

Rogatsky E, et al. Sensitive quantitative analysis of C-Peptide in human plasma by 2-dimensional liquid chromatography-mass spectrometry isotope-dilution assay. Clin. Chem. May 2006; 52(5): 872-879.
Kobayashi Y, et al. Human proinsulin C-peptide prevents proliferation of rat aortic smooth muscle cells cultured in high-glucose conditions. Diabetologia. Nov 2005; 48(11): 2396-2401.
Munte CE, et al. Solution structure of human proinsulin C-peptide. FEBS J. Aug 2005; 272(16): 4284-4293.

Full Name

C-Peptide (3-33), human

Sequence
(one-letter code)

EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ

Sequence
(three-letter code)

{GLU}{ALA}{GLU}{ASP}{LEU}{GLN}{VAL}{GLY}{GLN}{VAL}
{GLU}{LEU}{GLY}{GLY}{GLY}{PRO}{GLY}{ALA}{GLY}{SER}
{LEU}{GLN}{PRO}{LEU}{ALA}{LEU}{GLU}{GLY}{SER}{LEU}
{GLN}

Description

C-Peptide is a byproduct of insulin production, usually by the pancreas. The level of C-peptide can be used as a gauge of how much insulin is being produced in the body. The amount of C-peptide in the blood can indicate the presence or absence of disease. Abnormally low amounts of C-peptide in the blood suggest that insulin production is too low or absent because of type I diabetes, also known as juvenile or insulin-dependent diabetes. Abnormally high amounts of C-peptide warn of the possible presence of insulinoma tumors, which secrete insulin.

Solubility

Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out any smaller portion of the contents.

Formula

C₁₂₉H₂₁₁N₃₅O₄₈

M.W.

3020.26

Cas

33017-11-7

Purity

>95%

Storage

Store at -20�C. Keep container tightly closed.

* For Non-Clinical Research Use Only *


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