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Apelin-13, bovine, human

Cat. No. Size Price Figures
RP11221-0.5 mg
 		0.5 mg
$ 38.00
MS:  20060721145600  (PDF)
HPLC:  20060721145621  (PDF)
MSDS:  20080702213644  (PDF)
PROTOCOL:  20100407015038  (PDF)


References:
  • Lee DK, et al. Modification of the terminal residue of apelin-13 antagonizes its hypotensive action. Endocrinology. Jan 2005; 146(1): 231-236.
  • Jaszberenyi M, et al. Behavioral, neuroendocrine and thermoregulatory actions of apelin-13. Neuroscience. 2004; 129(3): 811-816.
  • Sunter D, et al. Intracerebroventricular injection of apelin-13 reduces food intake in the rat. Neurosci. Lett. Dec 2003; 353(1): 1-4.
Full Name
Apelin-13, bovine, human
Alias Apelin13; Apelin-13
Sequence
(one-letter code)		 QRPRLSHKGPMPF
Sequence
(three-letter code)		{GLN}{ARG}{PRO}{ARG}{LEU}{SER}{HIS}{LYS}{GLY}{PRO}
{MET}{PRO}{PHE}
DescriptionThe apelin peptide was recently discovered and demonstrated to be the endogenous ligand for the G protein-coupled receptor APJ, a purative receptor protein related to the angiotensin receptor (AT1). Apelin-13 exerts an acidification-rate-promoting activity in the CHO cells expressing the APJ receptor with a median effective concentration (EC50) value of the 0.37 nM. Apelin-13 blocks HIV-1 and HIV-2 entry into cells expressing the APJ receptor.
SolubilityThe peptide is soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
FormulaC69H111N22O16S
M.W.1536.8
Purity> 95%
StorageBefore use, store the peptide in the DRY form at 0-5°C. For best and most repeatable results, rehydrate the peptide immediately before use. Do not re-freeze any unused portions.
* For Non-Clinical Research Use Only *
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