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Parasin I

Cat. No. Size Price Figures
RP11233-0.5 mg
 		0.5 mg
$ 90.25
HPLC:  20060721145621  (PDF)
MS:  20060721145600  (PDF)
MSDS:  20080702215924  (PDF)


References:
  • Cho JH, et al. Cathepsin D produces antimicrobial peptide parasin I from histone H2A in the skin mucosa of fish. FASEB. J. Mar 2002; 16(3): 429-431.
  • Park IY, et al. Parasin I, an antimicrobial peptide derived from histone H2A in the catfish, Parasilurus asotus. FEBS. Lett. Oct 1998; 437(3): 258-262.
Full Name
Parasin I
Alias ParasinI; Parasin 1; Parasin1
Sequence
(one-letter code)		 KGRGKQGGKVRAKAKTRSS
Sequence
(three-letter code)		{LYS}{GLY}{ARG}{GLY}{LYS}{GLN}{GLY}{GLY}{LYS}{VAL}
{ARG}{ALA}{LYS}{ALA}{LYS}{THR}{ARG}{SER}{SER}
DescriptionParasin I is a potent 19-residue antimicrobial peptide isolated from the skin mucus of wounded catfish (Parasilurus asotus). Eighteen of the 19 residues in parasin I are identical to the N-terminus of buforin I, a 39-residue antimicrobial peptide derived from the N-terminus of toad histone H2A. This implies that parasin I is cleaved off of the N-terminus of catfish histone H2A. Parasin I shows strong antimicrobial activity, about 12-100 times as strong as magainin 2, against a wide spectrum of microorganisms, without any hemolytic activity. Furthermore, parasin I shows good antimicrobial activity against fish-specific bacterial pathogens.
FormulaC82H154N34O24
M.W.2000.3
Purity> 95%
StorageStore at -20°C
* For Non-Clinical Research Use Only *


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