| Cat. No. |
Size |
Price |
Figures |
|---|
RP11233-0.5 mg
| 0.5 mg | $ 90.25 | HPLC: 20060721145621 (PDF)
MS: 20060721145600 (PDF)
MSDS: 20080702215924 (PDF)
References:
- Cho JH, et al. Cathepsin D produces antimicrobial peptide parasin I from histone H2A in the skin mucosa of fish. FASEB. J. Mar 2002; 16(3): 429-431.
- Park IY, et al. Parasin I, an antimicrobial peptide derived from histone H2A in the catfish, Parasilurus asotus. FEBS. Lett. Oct 1998; 437(3): 258-262.
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| Full Name | |
| Alias |
ParasinI; Parasin 1; Parasin1 |
Sequence
(one-letter code) |
KGRGKQGGKVRAKAKTRSS | Sequence
(three-letter code) | {LYS}{GLY}{ARG}{GLY}{LYS}{GLN}{GLY}{GLY}{LYS}{VAL}
{ARG}{ALA}{LYS}{ALA}{LYS}{THR}{ARG}{SER}{SER} |
|---|
| Description | Parasin I is a potent 19-residue antimicrobial peptide isolated from the skin mucus of wounded catfish (Parasilurus asotus). Eighteen of the 19 residues in parasin I are identical to the N-terminus of buforin I, a 39-residue antimicrobial peptide derived from the N-terminus of toad histone H2A. This implies that parasin I is cleaved off of the N-terminus of catfish histone H2A. Parasin I shows strong antimicrobial activity, about 12-100 times as strong as magainin 2, against a wide spectrum of microorganisms, without any hemolytic activity. Furthermore, parasin I shows good antimicrobial activity against fish-specific bacterial pathogens.
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| Formula | C82H154N34O24 |
|---|
| M.W. | 2000.3 |
|---|
| Purity | > 95% |
|---|
| Storage | Store at -20°C |
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