Iwata M, et al. Angiotensin-(1-7) binds to specific receptors on cardiac fibroblasts to initiate antifibrotic and antitrophic effects. Am J Physiol Heart Circ Physiol. Dec 2005; 289(6): H2356-H2363.
Santos RA, et al. Impairment of in vitro and in vivo heart function in angiotensin-(1-7) receptor MAS knockout mice. Hypertension. May 2006; 47(5): 996-1002.
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Full Name
A-779
Sequence (one-letter code)
DRVYIHA
Sequence (three-letter code)
{ASP}{ARG}{VAL}{TYR}{ILE}{HIS}{d-ALA}
Description
A-779 is a potent and selective Ang (1-7) antagonist. A-779 antagonizes several actions of Ang (1-7), including A-779's antidiurectic effect and the changes in MAP produced by Ang (1-7) microinjection into the dorsomedial or ventrolateral medulla.
Formula
C39H60N12O11
M.W.
873
Purity
> 95%
Storage
Store at -20°C
* For Non-Clinical Research Use Only *
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