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[Sar1]-Angiotensin II

Cat. No. Size Price Figures
RP11270-5 mg
 		5 mg
$ 23.75
HPLC:  20060721145622  (PDF)
MS:  20060721145601  (PDF)
MSDS:  20080911225753  (PDF)


References:
  • Ahmed SB, et al. Effects of oral contraceptive use on the renal and systemic vascular response to angiotensin II infusion. J. Am. Soc. Nephrol. Mar 2004; 15(3): 780-786.
  • Lindley TE, et al. Superoxide is involved in the central nervous system activation and sympathoexcitation of myocardial infarction-induced heart failure. Circ. Res. Feb 2004; 94(3): 402-409.
  • Tan J, et al. Increases in brain and cardiac AT1 receptor and ACE densities after myocardial infarct in rats. Am. J. Physiol. Heart Circ. Physiol. May 2004; 286(5): H1665-1671.
Full Name
[Sar1]-Angiotensin II
Alias Angiotensin II; Angiotensin 2; AngII; Ang2
Sequence
(three-letter code)		SAR-ARG-VAL-TYR-ILE-HIS-PRO-PHE
DescriptionAngiotensin-II receptor antagonists (or blockers) are a newer class of antihypertensive agents. These drugs are selective for angiotensin II (type 1 receptor); unlike angiotensin-converting enzyme inhibitors, they do not inhibit bradykinin metabolism or enhance prostaglandin synthesis. Angiotensin-II receptor antagonists are well tolerated. Cough occurs much less often with these agents than with angiotensin-converting enzyme inhibitors, and they do not adversely affect lipid profiles or cause rebound hypertension after discontinuation. Clinical trials indicate that angiotensin-II receptor antagonists are effective and safe in the treatment of hypertension. Their use in congestive heart failure and renal disease is under investigation.
SolubilitySoluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
FormulaC49H71N13O10
M.W.1002.2
Purity> 95%
StorageBefore using, store the peptide in the DRY form at 0-5°C. For best and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions.
* For Non-Clinical Research Use Only *
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