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α-Endorphin

Cat. No. Size Price Figures
RP11328-1 mg
1 mg
$ 42.75
HPLC:  20060721145622  (PDF)
MS:  20060721145602  (PDF)
MSDS:  20080714051912  (PDF)

STRUCTURE:
α-Endorphin structure
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References:
  • Entschladen F, et al. Inhibition of cell migration via G protein-coupled receptors to opioid peptides and angiotensin. Ann. N. Y. Acad. Sci. Dec 2004; 1028: 320-328.
  • Gupta DS, Gintzler AR. Influence of ovarian sex steroids on spinal methionine-enkephalin release: comparison with dynorphin reveals asymmetrical regulation. J. Pharmacol. Exp. Ther. Feb 2003; 304(2): 738-744.
  • Rodan AR, et al. Functional dissection of neuroanatomical loci regulating ethanol sensitivity in Drosophila. J. Neurosci. Nov 2002; 22(21): 9490-9501.
Full Name
α-Endorphin
Alias LPH (61-76); β-Lipotropin (61-76), αEndorphin; a-Endorphin; aEndorphin; alpha-Endorphin; alphaEndorphin; βLipotropin; b-Lipotropin; bLipotropin; beta-Lipotropin; betaLipotropin
Sequence
(one-letter code)
YGGFMTSEKSQTPLVT
Sequence
(three-letter code)
{TYR}{GLY}{GLY}{PHE}{MET}{THR}{SER}{GLU}{LYS}{SER}
{GLN}{THR}{PRO}{LEU}{VAL}{THR}
Descriptionα-Endorphin is the 1-16 fragment of β-Endorphin. α-Endorphin is a substrate for transglutaminase and both α-Endorphin and α-Endorphin's acetylated form are found in intermediate and anterior lobes of the pituitary. α-Endorphin appears to bind to neuronal opiate receptors, but does not bind to β-Endorphin receptors in lymphocytes, vasculature, or vas deferens. Stimulatory effects on immune system function have been reported.
SolubilitySoluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents.
FormulaC77H120N18O26S1
M.W.1745.95
Cas59004-96-5
Purity>95%
StorageBefore use, store α-Endorphin in the DRY form at 0-5°C. For best and most repeatable results, rehydrate the peptide immediately before use. Do not re-freeze any unused portions.
* For Non-Clinical Research Use Only *
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