Cai YH, et al. Abrogation of Functional Selectin-Ligand Expression Reduces Migration of Pathogenic CD8+ T Cells into Heart. J.Immunol. Jun 2006; 176(11): 6568-6575.
Miyao N, et al. Various adhesion molecules impair microvascular leukocyte kinetics in ventilator-induced lung injury. Am.J.Physiol.Lung.Cell.Mol.Physiol. Jun 2006; 290(6): L1059-1068.
Loesch K, et al. Janus kinase 2 influences growth hormone receptor metalloproteolysis. Endocrinology. Jun 2006; 147(6): 2839-2849.
L-selectin is important for lymphocyte homing and adhesion to high endothelial cells of post capillary venules of peripheral lymph nodes. Moreover, this adhesion molecule contributes greatly to the capture of leukocytes during the early phases of the adhesion cascade. Following capture, L-selectin is shed from the leukocyte surface after chemoattractant stimulation. L-selectin interacts with three known counter receptors or ligands, MAdCAM-1, GlyCAM-1, and CD34. In conjunction with other molecules, L-selectin's function and influence in the adhesion cascade has been under scrutiny in many experiments using gene-targeted mice.
Formula
C62H106N16O18S2
M.W.
1427.8
Purity
> 95%
Storage
Store at -20°C.
* For Non-Clinical Research Use Only *
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