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[D-Trp11]-Neurotensin

Cat. No. Size Price Figures
RP11887-5 mg
5 mg
$ 95.00
MSDS:  20080715223538  (PDF)


References:
  • Crocker SJ, et al. Inhibition of calpains prevents neuronal and behavioral deficits in an MPTP mouse model of Parkinson's disease. J. Neurosci. May 2003; 23(10):4081-4091.
  • Binder EB, et al. Neurotensin and dopamine interactions. Pharmacol. Rev. Dec 2001; 53(4):453-486.
Full Name
[D-Trp11]-Neurotensin
Sequence
(one-letter code)
PELYENKPRRPwIL
Sequence
(three-letter code)
{pGLU}{LEU}{TYR}{GLU}{ASN}{LYS}{PRO}{ARG}{ARG}{PRO}
{d-TRP}{ILE}{LEU}
Description[D-Trp11]-Neurotensin is a neurotensin antagonist in which tyrosine 11 has been substituted by a tryptophan, which led to the incorporation of one or two iodine atoms on the single tyrosine residue in position 3.
SolubilitySoluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
FormulaC80H122N22O19
M.W.1695.96
Cas75644-95-0
Purity> 95%
StorageStore at -20°C. Keep tightly closed. Store in a cool dry place.
NotesNeurotensin analog that acts as a specific antagonist of Neurotensin in perfused rat hearts but acts as a full agonist in guinea pig atria and rat stomach strips
* For Non-Clinical Research Use Only *
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