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RGD-4C

Cat. No. Size Price Figures
RP12818-1 mg
1 mg
$ 332.50
MSDS:  20080703045444  (PDF)


References:
  • Kim JW, Lee HS. Tumor targeting by doxorubicin-RGD-4C peptide conjugate in an orthotopic mouse hepatoma model.Int. J. Mol. Med. Oct 2004; 14(4): 529-535.
  • Wang M, et al. Adenoviruses with an RGD-4C modification of the fiber knob elicit a neutralizing antibody response but continue to allow enhanced gene delivery. Gynecol. Oncol. Feb 2005; 96(2): 341-348.
  • Souza GR, et al. Networks of gold nanoparticles and bacteriophage as biological sensors and cell-targeting agents.Proc. Natl. Acad. Sci. U.S.A. Jan 2006; 103(5): 1215-1220.
RP12818-5 mg
5 mg
$ 1368.00
Full Name
RGD-4C
Sequence
(one-letter code)
ACDCRGDCFCG (Disulfide bridge: 2-10 and 4-8)
Sequence
(three-letter code)
{ALA}{CYS}{ASP}{CYS}{ARG}{GLY}{ASP}{CYS}{PHE}{CYS}
{GLY}
Chemical Bridge2-10 and 4-8
DescriptionRGD-4C is a double cyclic peptide that can bind preferentially to integrins at sites of tumor angiogenesis and inflamed synovium in vivo, and can be internalized into targeted cells. Novel applications include the coupling of RGD-4C to proapoptotic domains to treat tumors and inflammatory arthritis, and to radioactive labels for the broad spectrum imaging of tumor tissue.
FormulaC42H60N14O16S4
M.W.1145.3
Purity> 95%
StorageStore at -20°C. Keep tightly closed. Store in a cool dry place.
* For Non-Clinical Research Use Only *

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