Sicard F, et al. Neuroendocrine regulation of frog adrenocortical cells by neurotensin. Ann. N. Y. Acad. Sci. Apr 2005; 1040: 200-205.
Belmeguenai A, et al. Neurotensin stimulates both calcium mobilization from inositol trisphosphate-sensitive intracellular stores and calcium influx through membrane channels in frog pituitary melanotrophs.
Endocrinology. Dec 2003; 144(12): 5556-5567.
The primary structure of frog neurotensin (fNT) has recently been determined and it has been shown that fNT is a potent stimulator of -MSH secretion by frog pituitary melanotropes. Frog neurotensin is a potent stimulator of the electrical activity of frog pituitary melanotropes, and the electrophysiological response evoked by frog neurotensin can be accounted for by activation of a G(q/11)-protein-coupled receptor subtype whose pharmacological profile shares similarities with those of mammalian NTS1 and nts2 receptors.
Formula
C70H115N23O17
M.W.
1550.88
Purity
> 95%
Storage
Store at -20°C. Keep tightly closed. Store in a cool dry place.
* For Non-Clinical Research Use Only *
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