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| N-Boc-Phe-Leu-Phe-Leu-Phe |
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| Cat. No. |
Size |
Price |
Figures |
RP12950-5 mg
| 5 mg | $ 28.50 | HPLC: 20060721145624 (PDF) MS: 20060721145603 (PDF) MSDS: 20080703230454 (PDF) STRUCTURE:
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References:
- Fillion I, et al. Role of chemokines and formyl peptides in pneumococcal pneumonia-induced monocyte/macrophage recruitment. J Immunol. Jun 2001; 166(12): 7353-7361.
- VanCompernolle SE, et al. Expression and function of formyl peptide receptors on human fibroblast cells. J Immunol. Aug 2003; 171(4): 2050-2056.
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| Full Name | | N-Boc-Phe-Leu-Phe-Leu-Phe |
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| Alias |
Formylpeptide receptor antagonist |
Sequence (three-letter code) | BOC-PHE-LEU-PHE-LEU-PHE | | Description | As a well-known FPR antagonist, formyl peptide receptor antagonist Boc-Phe-Leu-Phe-Leu-Phe is used extensively in FPR research. In regard to neutrophils, it was found that treatment of mice with Boc-PLPLP results in 40% reduction in neutrophil counts recovered in bronchoalveolar lavage fluid, compared with infected mice receiving placebo. |
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| Solubility | The peptide is insoluble in water. It is soluble in 50% MeOH. |
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| Formula | C44H59N5O8 | | M.W. | 785.51 | | Purity | > 95% | | Storage | Store the peptide at -20°C. Keep container tightly close. | | Notes | Chemotactic inhibitor |
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