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N-Boc-Phe-Leu-Phe-Leu-Phe

Cat. No. Size Price Figures
RP12950-5 mg
 		5 mg
$ 28.50
HPLC:  20060721145624  (PDF)
MS:  20060721145603  (PDF)
MSDS:  20080703230454  (PDF)

STRUCTURE:
BOC-PLPLP structure
Zoom

References:
  • Fillion I, et al. Role of chemokines and formyl peptides in pneumococcal pneumonia-induced monocyte/macrophage recruitment. J Immunol. Jun 2001; 166(12): 7353-7361.
  • VanCompernolle SE, et al. Expression and function of formyl peptide receptors on human fibroblast cells. J Immunol. Aug 2003; 171(4): 2050-2056.
Full Name
N-Boc-Phe-Leu-Phe-Leu-Phe
Alias Formylpeptide receptor antagonist
Sequence
(three-letter code)		BOC-PHE-LEU-PHE-LEU-PHE
DescriptionAs a well-known FPR antagonist, formyl peptide receptor antagonist Boc-Phe-Leu-Phe-Leu-Phe is used extensively in FPR research. In regard to neutrophils, it was found that treatment of mice with Boc-PLPLP results in 40% reduction in neutrophil counts recovered in bronchoalveolar lavage fluid, compared with infected mice receiving placebo.
SolubilityThe peptide is insoluble in water. It is soluble in DMSO.
FormulaC44H59N5O8
M.W.785.51
Purity> 95%
StorageStore the peptide at -20°C. Keep container tightly close.
NotesChemotactic inhibitor
* For Non-Clinical Research Use Only *


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