| Cat. No. |
Size |
Price |
Figures |
|---|
RP13035-5 mg
| 5 mg | $ 95.00 | HPLC: 20050919140132 (PDF)
MS: 20050919140154 (PDF)
MSDS: 20070409044922 (PDF)
References:
- Polianova MT, et al. Chemokine receptor-5 (CCR5) is a receptor for the HIV entry inhibitor peptide T (DAPTA). Antiviral Res. Aug 2005; 67(2): 83-92.
- De Dios AC, et al. NMR studies of peptide T, an inhibitor of HIV infectivity, in an aqueous environment. J. Pept. Sci. Oct 2004; 10(10): 622-630.
- Ruff MR, et al. Update on D-ala-peptide T-amide (DAPTA): a viral entry inhibitor that blocks CCR5 chemokine receptors. Current HIV research. Jan 2003; 1(1): 51-67.
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|---|
| Full Name | |
Sequence
(one-letter code) |
ASTTTNYT |
Sequence
(three-letter code) | {D-ALA}{SER}{THR}{THR}{THR}{ASN}{TYR}{THR} |
|---|
| Description | Peptide T is a chain of eight amino acids. It shares sequence homology with HIV envelope protein gp120. Peptide T is potentially useful as antiviral agent in AIDS therapy. Peptide T is a synthetically produced protein derived from gp120--the protein on the surface of HIV particles that binds to the CD4 molecule on the surface of some human cells. Peptide T was discovered in 1986 when scientists were screening for gp120-derived peptides that might block HIV infection.
|
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| Solubility | Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weigh out a smaller portion of the contents. |
|---|
| Formula | C35H55N9O16 |
|---|
| M.W. | 857.87 |
|---|
| Purity | > 95% |
|---|
| Storage | Before use, store the peptide dry at 0-5°C. For best and most repeatable results, rehydrate the peptide immediately before use. Do not re-freeze any unused portions. |
