
| Cat. No. |
Size |
Price |
Figures |
RP13446-0.2 mg
| 0.2 mg | $ 118.75 | MSDS: 20080827052025 (PDF) EXAMPLE:
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References:
- Page AJ, et al. Modulation of gastro-oesophageal vagal afferents by galanin in mouse and ferret. J. Physiol. Mar 2005; 563(Pt 3): 809-819.
- Sarnelli G, et al. Inhibitory effects of galanin on evoked [Ca2+]i responses in cultured myenteric neurons. Am. J. Physiol. Gastrointest. Liver Physiol. Jun 2004; 286(6): G1009-1014.
- Seth A, et al. Galanin-like peptide stimulates the release of gonadotropin-releasing hormone in vitro and may mediate the effects of leptin on the hypothalamo-pituitary-gonadal axis. Endocrinology. Feb 2004; 145(2): 743-750.
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| Full Name | |
Sequence (one-letter code) |
GWTLNSAGYLLGPHALDSHRSFQDKHGLA-NH2 | Sequence (three-letter code) | {GLY}{TRP}{THR}{LEU}{ASN}{SER}{ALA}{GLY}{TYR}{LEU} {LEU}{GLY}{PRO}{HIS}{ALA}{LEU}{ASP}{SER}{HIS}{ARG} {SER}{PHE}{GLN}{ASP}{LYS}{HIS}{GLY}{LEU}{ALA} | | C-Terminal | NH2 |
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| Description | Galanin is a neuropeptide which is not a member of any known family of neuropeptides. Galanin's actions are mediated via Gi-protein-coupled receptors and ion channels, usually producing inhibition of secretion of a transmitter or hormone in the nervous and endocrine system. In many respects, these inhibitory actions of galanin remind us of those of gamma-aminobutyric acid (GABA) and of neuropeptide Y (NPY). Galanin coexists with GABA, noradrenaline, 5-hydroxytryptamine (5-HT), and NPY in several regions of the brain. |
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| Solubility | Soluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents. |
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| Formula | C141H211N43O40 | | M.W. | 3148.46 | | Purity | > 95% | | Storage | Before using, store the peptide in the DRY form at 0 - 5°C. For best and repeatable results, rehydrate the peptide immediately before using. Do not re-freeze any unused portions. |
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