Alevizaki M, et al. High plasma amylin/islet amyloid polypeptide levels in patients with residual medullary thyroid carcinoma after total thyroidectomy. Eur. J. Endocrinol. Nov 2001; 145(5): 585-589.
Henseleit KD, et al. NKX6 transcription factor activity is required for alpha- and beta-cell development in the pancreas. Development. Jul 2005; 132(13): 3139-3149.
Wickner RB, et al. Prions: proteins as genes and infectious entities. Genes Dev. Mar 2004; 18(5): 470-485.
Amylin is produced in the pancreas beta cells and coreleased with insulin. Amylin's amino acid sequence shows great homology with CGRP. Amylin has been shown to reverse insulin inhibition of hepatic gluconeogenesis and to inhibit muscle uptake of glucose.
Solubility
Insoluble in water. Dissolve peptide with 10% Acetonitrile in water.
Formula
C165H272N52O54S2
M.W.
3912.42
Purity
> 95%
Storage
Lyophilized powder may be stored at 4°C for short-term only. Reconstitute to nominal volume by adding sterile 40-50% glycerol and store at -20°C. Reconstituted product is stable for 24 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Notes
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
* For Non-Clinical Research Use Only *
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