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Eptifibatide

Cat. No. Size Price Figures
RP17308-10 mg
 		10 mg
$ 165.00
MSDS:  20080915214838  (PDF)

STRUCTURE:
Eptifibatide structure
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References:
  • Coons JC, Barcelona RA et al. Eptifibatide-associated acute, profound thrombocytopenia. Ann Pharmacother. Feb 2005;39(2):368-72.
  • Dalby M, Montalescot G et al. Eptifibatide provides additional platelet inhibition in non-ST-elevation myocardial infarction patients already treated with aspirin and clopidogrel. Results of the platelet activity extinction in non-Q-wave myocardial infarction with aspirin, clopidogrel, and eptifibatide (PEACE) study. J Am Coll Cardiol.Jan 2004;43(2):162-8.
  • Gurbel PA, Bliden KP et al. Clopidogrel loading with eptifibatide to arrest the reactivity of platelets: results of the Clopidogrel Loading With Eptifibatide to Arrest the Reactivity of Platelets (CLEAR PLATELETS) study. Circulation. Mar 2005;111(9):1153-9.
Full Name
Eptifibatide
Alias Integrilin
Sequence
(three-letter code)		MPA-ARG-GLY-ASP-TRP-PRO-CYS-NH2
C-TerminalNH2
Chemical BridgeMpa1-Cys7
DescriptionEptifibatide is a cyclic heptapeptide containing six amino acids and one mercaptopropionyl (des-amino cysteinyl) residue. An interchain disulfide bridge is formed between the cysteine amide and the mercaptopropionyl moieties. Chemically it is N6 -(aminoiminomethyl)-N2 -(3-mercapto-1-oxopropyl-L- lysylglycyl-L-a-aspartyl- L-tryptophyl-L -prolyl-L-cysteinamide, cyclic (1Ø6)-disulfide. Eptifibatide binds to the platelet receptor glycoprotein (GP) IIb/IIIa of human platelets and inhibits platelet aggregation.
FormulaC35H19N11O9S2
M.W.831.96
Cas188627-80-7
Purity> 95%
StorageStore at -20°C. Keep tightly closed. Store in a cool dry place.
* For Non-Clinical Research Use Only *

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