| Cat. No. |
Size |
Price |
Figures |
RP17317-1 mg
| 1 mg | $ 66.00 | STRUCTURE:
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References:
- Espeseth AS, Felock P et al. HIV-1 integrase inhibitors that compete with the target DNA substrate define a unique strand transfer conformation for integrase. Proc Natl Acad Sci U S A. Oct 2000;97(21):11244-9.
- Vandegraaff N, Kumar R et al. Specific inhibition of human immunodeficiency virus type 1 (HIV-1) integration in cell culture: putative inhibitors of HIV-1 integrase. Antimicrob Agents Chemother. Sep 2001;45(9):2510-6.
- David CA, Middleton T et al. Microarray compound screening (microARCS) to identify inhibitors of HIV integrase. J Biomol Screen. Jun 2002;7(3):259-66.
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| Full Name | | HIV Integrase Protein Inhibitor(1) |
|
Sequence (one-letter code) |
HCKFWW |
Sequence (three-letter code) | {HIS}{CYS}{LYS}{PHE}{TRP}{TRP} |
| Description | HIV Integrase Protein Inhibitor inhibit integration and viral replication in cells. These compounds exhibit the unique ability to inhibit the strand transfer activity of integrase in the absence of an effect on 3' end processing. |
|---|
| Formula | C46H55N11O7S |
| M.W. | 906.07 |
| Purity | > 95% |
| Storage | Store at -20°C. Keep tightly closed. Store in a cool dry place. |