GenScript Catalog Peptide: HIV Protease Substrate (RP17318)

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HIV Protease Substrate

Cat. No.

Size

Price

Figures

RP17318-1 mg

1 mg

$ 66.00

STRUCTURE:

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References:

Kupiec JJ, Hazebrouck S et al. Conversion of thymidylate synthase into an HIV protease substrate. J Biol Chem. Aug 1996;271(31):18465-70.
Katoh E, Louis JM et al. A solution NMR study of the binding kinetics and the internal dynamics of an HIV-1 protease-substrate complex. Protein Sci. Jul 2003;12(7):1376-85.

Full Name

HIV Protease Substrate

Sequence
(one-letter code)

AC-ARVLAEA-NH₂

Sequence
(three-letter code)

AC-{ALA}{ARG}{VAL}{LEU}{ALA}{GLU}{ALA}-NH₂

C-Terminal

NH₂

Description

The insertion of Human immunodeficiency virus type 1 (HIV-1) protease substrate sequences into the permissive sites converted TS to an HIV-1 protease substrate, and the in vivo cleavage of these insertions by the cloned HIV-1 protease conferred a thymidylate synthase-deficient phenotype in some of our E. coli mutant strains. The permissive sites are located in regions of the TS protein not essential for enzyme activity and accessible to cleavage by HIV protease.

Purity

> 95%

Storage

Store at -20°C. Keep tightly closed. Store in a cool dry place.

N-Terminal

* For Non-Clinical Research Use Only *

Precast Gels

Code	Name	Size	Price
RP17316	peptide : HIV p17 Gag (77-85)	1 mg	$ 99.00
GN076090	ORF Clone : Rad9	10 ug	$ 1462.50
GN156444	ORF Clone : EG208426	10 ug	$ 416.25
GN173001	ORF Clone : ckmt1	10 ug	$ 1567.50
GN245895	ORF Clone : LOC422507	10 ug	$ 1248.75

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