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Melanotan (MT)-II

Cat. No. Size Price Figures
RP17323-5 mg
 		5 mg
$ 82.00
MSDS:  20080516003316  (PDF)
HPLC:  20090531052330  (PDF)
MS:  20090531052342  (PDF)

STRUCTURE:
Melanotan II structure
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References:
  • Li G, Zhang Y et al. Unabated anorexic and enhanced thermogenic responses to melanotan II in diet-induced obese rats despite reduced melanocortin 3 and 4 receptor expression. J Endocrinol. Jul 2004;182(1):123-32.
  • van Dijk G, de Vries K et al. Reduced anorexigenic efficacy of leptin, but not of the melanocortin receptor agonist melanotan-II, predicts diet-induced obesity in rats. Endocrinology. Dec 2005;146(12):5247-56.
  • Wessells H, Hruby VJ et al. MT-II induces penile erection via brain and spinal mechanisms. Ann N Y Acad Sci. 2003 Jun;994:90-5.
Full Name
Melanotan (MT)-II
Alias MelanotanII; Melanotan 2; Melanotan2; MT-II; MTII; MT-2; MT2
Sequence
(three-letter code)		Ac-{NLE}{ASP}{HIS}{D-PHE}{ARG}{TRP}{LYS}-NH2
C-TerminalNH2
Chemical BridgeAsp2-Lys7
DescriptionMelanotan II is an analog of the peptide hormone alpha-melanocyte stimulating hormone (α-MSH). It shows strong melanotropic activity.
SolubilityThe peptide is soluble in water, 5 mg/ml.
FormulaC50H69N15O9
M.W.1024.18
Cas121062-08-6
Purity> 95%
StorageStore the peptide at -20°C. Keep container tightly closed.
N-TerminalAc
NotesAgonist of rat MC3-receptor (EC50=0.27 ± 0.23 nM) and mouse MC4-receptor (EC50 =0.057 ± 0.024 nM)
* For Non-Clinical Research Use Only *
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