Peptide Products
You are here:  Products » Peptide Products » Catalog Peptides - Hot Products »  γ-3-Melanocyte-Stimulating Hormone (MSH)   
 
A  B  C  D  E  F  G  H  I  J  K  L  M  N  O  P  Q  R  S  T  U  V  W  X  Y  Z  ALL  HotProducts  
Search by Catalog Number :(eg.RP01001)
Search by Name :(eg.Parathyroid Hormone (PTH))
Search by Sequence : (One letter code)
Search by Sequence : (Three letter code)

 
γ-3-Melanocyte-Stimulating Hormone (MSH)

Cat. No. Size Price Figures
RP17325-1 mg
 		1 mg
$ 165.00
MSDS:  20080918211938  (PDF)


References:
  • Denef C, et al. Gamma-MSH peptides in the pituitary: effects, target cells, and receptors. Ann. N. Y. Acad. Sci. Jun 2003; 994: 123-132.
  • Humphreys MH. Gamma-MSH, sodium metabolism, and salt-sensitive hypertension. Am. J. Physiol. Regul. Integr. Comp. Physiol. Mar 2004; 286(3): R417-430.
  • Klovins J, et al. Cloning of two melanocortin (MC) receptors in spiny dogfish: MC3 receptor in cartilaginous fish shows high affinity to ACTH-derived peptides while it has lower preference to gamma-MSH. Eur. J. Biochem. Nov 2004; 271(21): 4320-4331.
Full Name
γ-3-Melanocyte-Stimulating Hormone (MSH)
Alias γ3-MSH; g-3-MSH; g3MSH; gamma-3-MSH; gamma3-MSH, γ-Melanocyte Stimulating Hormone; γ3-Melanocyte Stimulating Hormone; g-3-Melanocyte Stimulating Hormone; g3Melanocyte Stimulating Hormone; gamma-3-Melanocyte Stimulating Hormone; gamma3-Melanocyte Stimulating Hormone
Sequence
(one-letter code)		 YVMGHFRWDRFGRRNGSSSSGVGGAAQ
Sequence
(three-letter code)		{TYR}{VAL}{MET}{GLY}{HIS}{PHE}{ARG}{TRP}{ASP}{ARG}
{PHE}{GLY}{ARG}{ARG}{ASN}{GLY}{SER}{SER}{SER}{SER}
{GLY}{VAL}{GLY}{GLY}{ALA}{ALA}{GLN}
DescriptionMelanocortin (MC) 3-MSH (Melanocyte-Stimulating Hormone) is believed to signal through the MC 3 receptor. It induces a sustained increase in intracellular free calcium levels ([Ca2+]i) in a subpopulation of pituitary cells. Most of the cells responding to 3-MSH express more than one pituitary hormone mRNA. The effect of 3-MSH is blocked by SHU9119, a MC3R and MC4R antagonist, in only 50% of the responsive cells, suggesting that in half of these cells the mediating receptor is not the MC3R. Low picomolar doses of 3-MSH increase [Ca2+]i in the growth hormone (GH)- and prolactin (PRL)-secreting GH3 cell line.
SolubilitySoluble in water. The contents of this vial have been accurately determined. Both the stopper and the vial have been siliconized. Do not attempt to weight out a smaller portion of the contents.
FormulaC126H188N44O37S
M.W.2943.19
Purity> 95%
StorageStore the peptide at -20°C. Keep container tightly closed. Store in a cool dry place.
* For Non-Clinical Research Use Only *
Related Products:
CodeNameSizePrice 
RP10644peptide : α-Melanocyte-Stimulating Hormone (MSH), amide1 mg
$ 23.75
5 mg
$ 57.00
RP10648 peptide : β-Melanocyte Stimulating Hormone (MSH), human1 mg
$ 90.25
RP10650peptide : γ-1-Melanocyte Stimulating Hormone (MSH), amide1 mg
$ 52.25
RP10658 peptide : [Nle4, D-Phe7]-α-Melanocyte Stimulating Hormone (MSH), amide1 mg
$ 66.50
5 mg
$ 266.00
RP17323peptide : Melanotan (MT)-II5 mg
$ 82.50




Our customer service is available 24 hours a day, Monday through Friday. You may contact us any time for assistance.