| Cat. No. |
Size |
Price |
Figures |
|---|
RP17328-1 mg
| 1 mg | $ 115.50 |
References:
- Cho JW, et al. Aberrant p16INK4A RNA transcripts expressed in hepatocellular carcinoma cell lines regulate pRb phosphorylation by binding with CDK4, resulting in delayed cell cycle progression. Liver Int. Jun 2003; 23(3): 194-200.
- Fahraeus R, et al. Inhibition of pRb phosphorylation and cell-cycle progression by a 20-residue peptide derived from p16CDKN2/INK4A. Curr Biol. Jan 1996; 6(1): 84-91.
|
|---|
| Full Name | |
| Alias |
[Ala92]-p16 fragment 84-103 |
Sequence
(one-letter code) |
DAAREGFLDTLVVLHRAGAR |
Sequence
(three-letter code) | {ASP}{ALA}{ALA}{ARG}{GLU}{GLY}{PHE}{LEU}{ASP}{THR}
{LEU}{VAL}{VAL}{LEU}{HIS}{ARG}{ALA}{GLY}{ALA}{ARG} |
|---|
| Description | Modified fragment from the third ankyrin-like repeat of p16 that binds to cdk4 and cdk6 and inhibits phosphorylation of the retinoblastoma gene product pRb mediated by cdk4-cyclin D.
|
|---|
| Formula | C93H155N31O26
|
|---|
| M.W. | 2123.42 |
|---|
| Cas | 189064-08-2 |
|---|
| Purity | > 95% |
|---|
| Storage | Store at -20°C.
|
