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EGFR (988-993) (Phospho-Tyr5)

Cat. No. Size Price Figures
RP20108-0.5 mg
 		0.5 mg
$ 73.50
MSDS:  20081110020455  (PDF)
HPLC:  20081110003753  (PDF)
MS:  20081110003843  (PDF)


References:
  • Peters, GH. et al. Biophysical J. 77, 505 (1999)
  • Choi, M. et al. Bull. Korean Chem. Soc. 20, 1126 (1999)
  • Sarmiento, M. et al. J. Biol. Chem. 273, 26368 (1998)
Full Name
EGFR (988-993) (Phospho-Tyr5)
Sequence
(one-letter code)		 DADE-pY-L
Sequence
(three-letter code)		{Asp}{Ala}{Asp}{Glu}{pTyr}{Leu}
DescriptionThis phosphotyrosil peptide sequence is derived from the autophosphorylation site (Tyr992) of epidermal growth factor receptor (EGFR 988-993). Using synthetic pTyr-containing peptides that correspond to natural phosphorylation sites in proteins, several groups have demonstrated that PTPases display a range of kcat/Km values for these relatively short peptide substrates. This peptide is a minimal (6 residues) peptide substrate for both the Yersinia PTPase and the mammalian PTP1. It is often complexed with the catalytically inactive protein-tyrosine phosphate 1B (PTP1B).
FormulaC31H45N6O17P
M.W.804.7
Purity95%
StorageStore GenScript EGFR (988-993) (Phospho-Tyr5) at -20°C.
* For Non-Clinical Research Use Only *


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