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| CMV Pp65 (UL83), CytomegaloVirus Antigen, Recombinant |
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| Catalog No. |
Size |
Price |
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Z00010-1 mg
| 1 mg | $ 1000.00 |
References:
- Yue Y, et al. Characterization and immunological analysis of the rhesus cytomegalovirus homologue (Rh112) of the human cytomegalovirus UL83 lower matrix phosphoprotein (pp65). J. Gen. Virol. Apr 2006; 87(Pt 4): 777-787.
- Fenwick F, et al. Immunohistochemical assessment of hepatitis C virus antigen in cholestatic hepatitis after liver transplantation. J. Clin. Pathol. Feb 2006; 59(2): 174-178.
- Plesa G, et al. Immunogenicity of cytopathic and noncytopathic viral vectors. J. Virol. Jul 2006; 80(13): 6259-6266.
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| Full Name | | CMV Pp65 (UL83), CytomegaloVirus Antigen, Recombinant |
| | Abbreviated Name-1 | CMV Pp65 |
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| Description | CytomegaloVirus (CMV) pp65 (UL83) is an E. coli-derived recombinant. The protein contains the CMV Pp65 (UL83) immunodominant regions. CMV-pp65 is purified by proprietary chromatographic techniques. The human cytomegalovirus UL99-encoded pp28 is a myristylated phosphoprotein and a constituent of the virion. The pp28 protein is positioned within the tegument of the virus particle, a protein structure that resides between the capsid and envelope. In the infected cell, pp28 is found in a cytoplasmic compartment derived from the Golgi apparatus, where the virus buds into vesicles to acquire its final membrane. |
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| Source | E. coli |
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| Purity | Protein is >95% pure as determined by 10% PAGE (Coomassie staining). |
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| Storage | Protein is shipped at ambient temperature. Upon arrival, store it at -20°C. |
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| Concentration | 1 mg/ml in 25 mM Tris-Hcl pH 7.2, 1 mM EDTA, 50% glycerol |
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| Stability | The protein will remain stable for five years if for stored frozen, and for one month if stored in solution at room temperature. |
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| Specificity | The protein is immunoreactive with the sera of CMV-infected individuals. |
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| Applications | The protein makes a good antigen in ELISA and western blots and an excellent antigen in the detection of CMV. It shows minimal specificity problems. |
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