| Catalog No. |
Size |
Price |
Figures |
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Z00145-1 mg
| 1 mg | $ 420.00 |
References:
- Grimaldi LM, et al. HTLV-I-associated myelopathy: oligoclonal immunoglobulin G bands contain anti-HTLV-I p24 antibody. Ann Neurol. Dec 1988; 24(6): 727-731.
- Stransky G, Gay S. Ultrastructural localization of HTLV-I gag proteins p19 and p24 by single and double immunogold labeling. J. Histochem. Cytochem. Feb 1991; 39(2): 185-191.
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| Full Name | | Human T-Lymphocyte Virus (HTLV)-1 p24 Core |
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| Abbreviated Name-1 | rHTLV-Ip24c |
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| Abbreviated Name-2 | Major core protein p24; gag polyprotein |
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| Description | GenScript Human T-Lymphocyte Virus (HTLV)-1 p24 Core is an E. coli-derived recombinant. The protein contains the full-length sequence of HTLV-I p24. Human T-lymphotropic virus (HTLV) belongs to the family Retroviridae, genus Deltaretrovirus. It is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma in adults and may also be involved in certain demyelinating diseases. Adult T-lymphotropic virus (ATLV) is a strain of this disease that effect primarily adults. Capsid protein p24 probably forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex. |
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| Source | E. coli |
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| Purity | Protein is >95% pure (as determined by HPLC-C4, and 10% PAGE). |
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| Storage | Reagent is shipped at ambient temperature. Freeze upon arrival. Store at -20°C. |
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| Concentration | 1.0 mg/ml in 50 mM Na-PO4, pH 6.0, containing 1 mM DTT and 1 mM EDTA |
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| Stability | The protein will remain stable for five years if stored frozen and for six months if stored in solution at 4°C. |
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| Specificity | The protein is immunoreactive with the sera of HTLV-I infected individuals. |
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| Applications | This protein makes a good antigen in ELISA and western blots and an excellent antigen in the early detection of HIV seroconvertors. It shows minimal specificity problems. |
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