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HTLV-1 p24 Core, Human T-Lymphocyte Virus Antigen, Recombinant

Catalog No. Size Price Figures
Z00145-1 mg
1 mg
$ 1000.00

References:
  • Grimaldi LM, et al. HTLV-I-associated myelopathy: oligoclonal immunoglobulin G bands contain anti-HTLV-I p24 antibody. Ann Neurol. Dec 1988; 24(6): 727-731.
  • Stransky G, Gay S. Ultrastructural localization of HTLV-I gag proteins p19 and p24 by single and double immunogold labeling. J. Histochem. Cytochem. Feb 1991; 39(2): 185-191.
Full Name
HTLV-1 p24 Core, Human T-Lymphocyte Virus Antigen, Recombinant
Abbreviated Name-1rHTLV-Ip24c
Abbreviated Name-2Major core protein p24; gag polyprotein
DescriptionGenScript Human T-Lymphocyte Virus (HTLV)-1 p24 Core is an E. coli-derived recombinant. The protein contains the full-length sequence of HTLV-I p24. Human T-lymphotropic virus (HTLV) belongs to the family Retroviridae, genus Deltaretrovirus. It is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma in adults and may also be involved in certain demyelinating diseases. Adult T-lymphotropic virus (ATLV) is a strain of this disease that effect primarily adults. Capsid protein p24 probably forms the conical core of the virus that encapsulates the genomic RNA-nucleocapsid complex.
SourceE. coli
PurityProtein is >95% pure (as determined by HPLC-C4, and 10% PAGE).
StorageReagent is shipped at ambient temperature. Freeze upon arrival. Store at -20°C.
Concentration1.0 mg/ml in 50 mM Na-PO4, pH 6.0, containing 1 mM DTT and 1 mM EDTA
StabilityThe protein will remain stable for five years if stored frozen and for six months if stored in solution at 4°C.
SpecificityThe protein is immunoreactive with the sera of HTLV-I infected individuals.
ApplicationsThis protein makes a good antigen in ELISA and western blots and an excellent antigen in the early detection of HIV seroconvertors. It shows minimal specificity problems.
* For Non-Clinical Research Use Only *
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