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| Heparanase (HPA)-1, human |
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| Catalog No. |
Size |
Price |
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Z00169-100 ng
| 100 ng | $ 420.00 | MSDS: 20080115212825 (PDF)
References:
- Ogishima T, Shiina H et al. Increased heparanase expression is caused by promoter hypomethylation and up-regulation of transcriptional factor early growth response-1 in human prostate cancer. Clin Cancer Res. Feb 2005;11(3):1028-36.
- Reiland J, Sanderson RD et al. Heparanase degrades syndecan-1 and perlecan heparan sulfate: functional implications for tumor cell invasion. J Biol Chem. Feb 2004;279(9):8047-55.
- de Mestre AM, Rao S et al. Early growth response gene 1 (EGR1) regulates heparanase gene transcription in tumor cells. J Biol Chem. Oct 2005;280(42):35136-47.
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| Full Name | | Heparanase (HPA)-1, human |
| | Abbreviated Name-1 | Heparanase 1 |
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| Abbreviated Name-2 | HPA1 |
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| Description | Heparanase (HPA)-1, human is produced in CHO cells. The protein is purified by several orthogonal chromatography steps. Heparanase is an endoglycosidase that degrades heparan sulfate chains of heparan sulfate proteoglycans, a key component of extracellular matrix and basement membranes. |
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| Source | Chinese Hamster Ovary Cells (CHO) |
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| Storage | Store at -20°C, avoid repeated freeze-thaw cycles. |
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| Formulation | 140 mM Tris buffer pH 8.5, 10% Glycerol, 2% LDS, 0.015% EDTA, 1.88% (v/v) of 1% Serva Blue G250 and 0.625% (v/v) of 1% Phenol red |
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| Concentration | 100 ng,1 μg /ml |
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| Applications | Positive control for western blot analysis |
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