| Catalog No. |
Size |
Price |
Figures |
|---|
Z02001-100 ug
| 100 ug | $ 340.00 |
References:
- Dauffy J, et al. The interferon-inducible gene, Ifi204, is transcriptionally activated in response to M-CSF, and its expression favors macrophage differentiation in myeloid progenitor cells. J Leukoc Biol. Jan 2006; 79(1): 173-183.
- Oksjoki R, et al. OxLDL-IgG immune complexes induce survival of human monocytes. Arterioscler Thromb Vasc Biol. Mar 2006; 26(3): 576-583.
- Clanchy FI, et al. Detection and properties of the human proliferative monocyte subpopulation. J Leukoc Biol. Apr 2006; 79(4): 757-766.
|
|---|
Z02001-1 mg
| 1 mg | $ 3000.00 |
|---|
| Full Name | | Macrophage Colony Stimulating Factor (M-CSF), human |
|
| Abbreviated Name-1 | Human recombinant M-CSF |
|---|
| Abbreviated Name-2 | Macrophage Colony Stimulating Factor |
|---|
| Description | Macrophage Colony Stimulating Factor (M-CSF), human is produced by mesenchymal cells, such as fibroblasts, macrophages, and endothelial cells. The stimulating factor (M-CSF) stimulates the survival, proliferation, and differentiation of hematopoietic cells of the monocyte-macrophage series. M-CSF binds to a specific high-affinity receptor. M-CSF is a disulfide-linked homodimer. |
|---|
| Source | Mesenchymal cells |
|---|
| M.W. | monomer 18,200 Da (reducing conditions), homodimer 30,300 Da (non-reducing conditions) |
|---|
| Purity | >97%, as determined by HPLC |
|---|
| Endotoxin Level | < 1.0 Endotoxin Unit (EU) per 1 µg as determined by the LAL method |
|---|
| Specific Activity | The ED50 < 5 ng/ml, determined by the dose-dependent stimulation of the proliferation of murine M-NSF-60 cells, has a specific activity of > 2×105 units/mg. |
|---|
| Storage | Lyophilized samples are stable for up to twelve months from date of delivery if stored at -20°C to -70°C. |
|---|
| Formulation | 100 µg M-CSF, 10 mg HSA, 60 mg mannitol |
|---|
| Reconstitution | It is recommended that sterile PBS be added to prepare a stock solution of no less than 1 µg/ml. |
|---|
| Sequence | MEEVSEYCSH MIGSGHLQSL QRLIDSQMET SCQITFEFVD QEQLKDPVCY LKKAFLLVQD IMEDTMRFRD NTPNAIAIVQ LQELSLRLKS CFTKDYEEHD KACVRTFYET PLQLLEKVKN VFNETKNLLD KDWNIFSKNC NNSFAECSSQ GHERQSEGS |
|---|
