| Catalog No. |
Size |
Price |
Figures |
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Z02010-1 mg
| 1 mg | $ 420.00 |
References:
- Decroly E, et al. The convertases furin and PC1 can both cleave the human immunodeficiency virus (HIV)-1 envelope glycoprotein gp160 into gp120 (HIV-1 SU) and gp41 (HIV-I TM). J. Biol. Chem. Apr 1994; 269(16): 12240-12247.
- VanCott TC, et al. Lack of induction of antibodies specific for conserved, discontinuous epitopes of HIV-1 envelope glycoprotein by candidate AIDS vaccines. J. Immunol. Oct 1995; 155(8): 4100-4110.
- Pincus SH, et al. Vaccine-specific antibody responses induced by HIV-1 envelope subunit vaccines. J. Immunol. Apr 1997; 158(7): 3511-3520.
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| Full Name | | Human Immunodeficiency Virus (HIV)-1 Envelope |
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| Abbreviated Name-1 | HIV-I envelope |
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| Description | E. coli-derived GenScript Human Immunodeficiency Virus (HIV)-1 Envelope spanning the C-Terminus of gp120 and most of gp41. Superior diagnostic reagent for HIV-1 and HIV type-O detection. Detects all HIV-1 and HIV-type O infected individuals responding to envelope proteins. |
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| Source | E. coli |
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| Purity | Protein is >95% pure as determined by 10% PAGE (coomassie staining). |
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| Storage | Protein is shipped at ambient temperature. Upon arrival, store at +4°C.
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| Concentration | •1 mg/ml in 50 mM Tris. pH8.0, containing 0.1% SDS, 5 mM DTT, and 2.5 mM EDTA. (Proper for ELISA)
•3 mg/ml in 8 M Urea, 20 mM Tris-HCl, 1 mM EDTA, 10 mM b-mercaptoethanol, pH8. (Proper for membrane applications)
•3 mg/ml in 10 mM Citrate pH3.0. (Proper for ELISA) |
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| Stability | Five years frozen. Four months in solution at room temperature. |
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| Specificity | Immunoreactive with all sera of HIV-1 and HIV-type O infected individuals and with 60-80% of HIV-2 infected individuals. |
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| Applications | Antigen in ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems. |
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